ISRCTN10817487进行中（未招募）未知
World Hip Trauma Evaluation - LIT: Lidocaine Intravenous Trial
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中（未招募）
- 入组人数
- 416
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Platform inclusion criteria:
- •1. Aged =60 years
- •2. Diagnosed with a hip fracture that in the opinion of the treating surgeon may benefit from surgical treatment
- •No additional specific inclusion criteria for LIT.
排除标准
- •Platform exclusion criteria.
- •1. Previous participation in the same randomised comparison
- •2. A second hip fracture (other side) while the patient is still enrolled in the Platform following their first hip fracture
- •Additional specific exclusion criteria for LIT:
- •1. Body weight estimated to be <40 kg or >100 kg
- •2. Known subdural haematoma
- •3. Known allergy to local anaesthetics
- •4. Severely impaired renal (eGFR <30 ml.min-1) or hepatic (based on clinical history) function
- •5. Patient has specific contraindications to lidocaine:
- •5.1. All grades of atrioventricular block; severe myocardial depression; sino-atrial disorders
- •5.2. Acute porphyria
- •5. 3. Current congestive cardiac failure
- •6. Concurrent participation in a clinical trial of a medicinal product or recent participation within 5 half-lives of the last dose of medicinal product
- •7. Local anaesthetic nerve block administered within the previous 6 hours
- •8. Known serum albumin <30 g/l
研究者
相似试验
进行中（未招募）
不适用
An investigation in people aged 60 years and over with a hip fracture to determine whether fixing the broken hip bone or replacing the hip joint gives the patient a better quality of life after 4 monthsMinimally displaced intracapsular hip fractureMusculoskeletal DiseasesFracture of neck of femurISRCTN28566489niversity of Oxford878
进行中（未招募）
Unknown
WHITE 14-PRESSURE 3: An investigation of people 60 years and over with a broken hip to determine whether using specialised heel pressure equipment can lower the number of people developing a pressure ulcer on the heel after surgeryISRCTN10696770niversity of Oxford3,102
已完成
不适用
World hip trauma evaluation fourTopic: Injuries & Emergencies, SurgerySubtopic: Injuries & Emergencies (all Subtopics), SurgeryDisease: Injuries & Emergencies, All SurgeryMusculoskeletal DiseasesProximal femur fractureISRCTN92825709niversity of Oxford1,128
进行中（未招募）
不适用
World Hip Trauma EvaluatioProximal femur fractureInjury, Occupational Diseases, PoisoningFracture of femurISRCTN63982700niversity of Oxford6,000
进行中（未招募）
不适用
WHITE 12-DUALITY: An investigation of people 65 years and over with a broken hip to determine whether using a hip replacement with modified mobility (Dual mobility cup) can reduce the rate of hip dislocation in the first year after hip fracture surgeryISRCTN11895196niversity of Oxford450