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Clinical Trials/NCT05768581
NCT05768581
Completed
Not Applicable

Effects of a Concurrent Home-based Training on Cardiorespiratory Fitness, Muscular Strength, Balance, Daily-life Activities and Body Composition in Obese Individuals

Istituto Auxologico Italiano1 site in 1 country132 target enrollmentOctober 1, 2022
ConditionsObesity

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Obesity
Sponsor
Istituto Auxologico Italiano
Enrollment
132
Locations
1
Primary Endpoint
Change from baseline cardiorespiratory fitness in number of steps performed at 10 weeks fitness
Status
Completed
Last Updated
8 months ago

Overview

Brief Summary

Ample evidence demonstrates the beneficial role of physical activity combined with a structured dietary plan to counteract obesity. International guidelines as the World Health Organization states that to improve fitness levels at least 150 min a week of physical activity at moderate intensity, combined with resistance training composed of 8-12 repetitions with an intensity of 60-70%1RM for each muscle group, are recommended. In this regard, a minimum dosage of 60-90 min of physical activity composed by aerobic exercises in alternation with resistance training protocols, allow a sequential development of cardiorespiratory fitness and muscular strength parameters avoiding potential interference effects. Interference may occur when strength and endurance stimuli both target opposite peripheral adaptations (e.g., hypertrophy vs. muscle capillarization) and this phenomenon seems to be particularly clear during adolescence. Nevertheless, the incorporation of different training stimuli within the same training session is called Concurrent Training. This training mode, thanks to the activation of two different metabolic pathways (e.g., aerobic and anaerobic), has a variety, beneficial effects in terms of muscle mass and strength development, body composition profile regulation and neuromotor function improvement. Concurrent Training seems to be effective not only in normal-weight subjects, but also in obese individuals, reporting positive adaptations on physical fitness and health status compared with a single-mode (i.e., aerobic or strength training). Therefore, the aim of this study is to detect the effects of a 10-week-Concurrent Training protocol compared with a single training modality on physical fitness, body composition and circadian rhythms in adult outpatients with obesity.

Registry
clinicaltrials.gov
Start Date
October 1, 2022
End Date
April 30, 2024
Last Updated
8 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Physical activity frequency minor of 2 days/week
  • BMI major of 30 kg/m2
  • informed consent signature

Exclusion Criteria

  • age over 65 years
  • knee or hip pain (visual analogue scale score \>7 arbitrary units
  • a history of hip, knee or foot replacement or osteoarthrosis
  • cardiac infarction
  • neurological impairments or any other clinical condition that affects the practice of physical activity

Outcomes

Primary Outcomes

Change from baseline cardiorespiratory fitness in number of steps performed at 10 weeks fitness

Time Frame: Up to 10 weeks

Maximum aerobic capacity using the two minute step test

Change from baseline strength in kilograms at 10 weeks

Time Frame: Up to 10 weeks

Maximum isometric handgrip strength using a dynamometer

Change from baseline postural control in arbitrary units at 10 weeks

Time Frame: Up to 10 weeks

Balance and postural control using the Balance Error Scoring System

Secondary Outcomes

  • Change from baseline weight in kilograms at 10 weeks(Up to 10 weeks)
  • Change from baseline circadian rhythm in arbitrary units at 10 weeks(Up to 10 weeks)
  • Change from baseline height in meters at 10 weeks(Up to 10 weeks)
  • Change from baseline waist circumference in centimeters at 10 weeks(Up to 10 weeks)
  • Change from baseline fat mass percentage at 10 weeks(Up to 10 weeks)

Study Sites (1)

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