STUDY ON THE ROLE OF ASPIRIN IN PREVENTING PRETERM BIRTH

Recruiting

Conditions: Factors influencing health status and contact with health services,

Registration Number: CTRI/2021/03/031734

Lead Sponsor: PGIMER

Brief Summary: Aspirin is a commonly prescribed drug in antenatal women at risk for preeclampsia.Secondary outcomes of studies have shown that aspirin given to women also lowered the incidence of preterm birth apart from having a protective role in preeclampsia.This study aims to see the effect of aspirin in reducing incidence of preterm birth in women at risk.Aspirin is a cheap intervention and could prove useful in low resource settings if found effective.

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: Female

Target Recruitment: 100

Inclusion Criteria

Antenatal Women between 6 to 16 weeks of gestation Singleton Pregnancy History of previous spontaneous preterm birth and/or PPROM or history of second trimester abortion.

Exclusion Criteria

Previous indicated preterm birth for maternal or fetal reasons Contraindications to aspirin use Major fetal malformations in current or previous pregnancy Multifetal gestation Moderate /severe anaemia Medical comorbidities Uterine anomalies and cervical insufficiency At risk for preeclampsia.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare incidence of preterm birth at less than 37 weeks of gestation between aspirin and non aspirin groups	9 months

Secondary Outcome Measures

Name	Time	Method
To compare maternal complications and neonatal outcomes between aspirin and non aspirin groups	9 months

Trial Locations

Locations (1): PGIMER,Chandigarh
🇮🇳
Chandigarh, CHANDIGARH, India
PGIMER,Chandigarh
🇮🇳Chandigarh, CHANDIGARH, India
Tanu Sharma
Principal investigator
8219051719
keepintouch.2008@rediffmail.com