JPRN-jRCTb040190123已完成1 期
Study of the safety concernig autolougaus adipose tissue-derived stem cells for osteoarthritis of knee joint. (autolougaus adipose tissue-derived stem cells for osteoarthritis of knee joint.)
Tsutsumi Mikihiro0 个研究点目标入组 5 人开始时间: 2020年3月3日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 5
研究概览
简要总结
In this study, knee osteoarhritis was treated with autologous Lipogems products. There were 5 females aged 56 to 63 years old (mean 60 years old), who were 2 as grade II, 2 as grade II and one as grade IV of (K-L). Clinical evaluation was performed at 1 week, 1, 3 and 6 months after the operation, and no adverse event was observed. Both VAS and KOOS were significantiy increased after surgery, suggesting that treatment with Lipogems products for patients with knee osteoarthraitis may be safe and useful.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 30age old 至 <= 85age old（—）
- 性别
- All
入选标准
- •1) 30 to 85 years of age
- •2) grade II-IV (Kellgren-Lawrence) by X-ray
- •3) persistent symptoms for more than 6 months
- •4) failure of conservative management
- •5) possibility general anesthesia
排除标准
- •1)History of active neoplasm and active inflammatory disease
- •2) severe symptom by cerebral infarction and pulmonary infarction
- •3) rheumatoid arthritis and gout
- •4) pregnancy or lactation
- •5) thrombocytopenia
- •6) participation in other clinical studies
- •7) positive test result against HIV, HBV, HCV, syphilis or HTLV-1
- •8) severe DM, heart failure or renal failure.
研究者
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