Multicenter, open-label, non-controlled trial of short-term high dose dexamethasone therapy as initial treatment for idiopathic thrombocytopenic purpura
- Conditions
- Idiopathic Thrombocytopenic Purpura
- Registration Number
- JPRN-UMIN000022415
- Lead Sponsor
- ATIONAL KYUSHU MEDICAL CENTER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 25
Not provided
1)Active malignancy at time of study entry 2)Concomitant treatment with anti-platelet and or anti-coagulant drugs 3)Concomitant severe psychiatric disorders 4)Women who are pregnant or breastfeeding 5)Cardiovascular diseases requiring treatment 6)Severe non-controlled, despite therapy, hypertension and diabetes 7)Liver and kidney function impairment (creatinine, ALT, AST >2 times upper normal limit) 8)HCVAb, HIVAb, HBsAg seropositive status 9)Chronic liver disease 10)Documented viral illness by the positivity of IgM, or vaccination both occurred one month before diagnosis 11)Intake of drugs not previously taken within one week before diagnosis 12) Active gastric ulcer. 13)Severe intracranial bleeding or GI bleeding 14)Presence of autoimmune hemolytic anemia 15) Continuous administration of steroid hormone or immunosuppressive agents for other disease. 16)Not appropriate for this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method