Oral Vitamin D Supplementation in Elderly Women
Not Applicable
Completed
- Conditions
- Optimal Vitamin D Administration
- Interventions
- Dietary Supplement: vitamin D twice dailyDietary Supplement: Vitamin D3 oil three times in a year
- Registration Number
- NCT00575835
- Lead Sponsor
- University of Helsinki
- Brief Summary
The aim of this study is to compare oral vitamin D supplementation administered in two different ways, namely either twice a day (800IU/d, 292000IU/y) or three times a year (97333IU every 4 months, 292000IU/y) in elderly women in combination with daily supplementation of calcium 1 gram. We will 1)compare the blood concentrations of 25 OH vitamin D in the two treatment groups amd monitor if a sufficient and safe concentration of 25OH D in blood can be maintained with these two treatments.2) Find out seasonal variation in vitamin D concentrations in these treatments. 3) Find out safety of these treatments
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 40
Inclusion Criteria
- Females
- 70-80 years
- Living in the community
Exclusion Criteria
- Renal disease
- Diseases that contraindicate vitamin D supplementation
- Medications affecting bone
- Malignancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 1 vitamin D twice daily - 2 Vitamin D3 oil three times in a year -
- Primary Outcome Measures
Name Time Method Blood 25 OH D vitamin concentrations 8 times during the year
- Secondary Outcome Measures
Name Time Method serum calcium, 24-hour calcium excretion in urine, creatinine clearance 8 times during the year
Trial Locations
- Locations (1)
Helsinki University Central Hospital, department of medicine, division of endocrinology
🇫🇮Helsinki, Finland