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ENDO GIA™ Stapler With ENDO GIA™ Reload With Tri-Staple™ Technology in a Pulmonary Resection

Not Applicable
Completed
Conditions
Lung Cancer
Interventions
Device: ENDO GIA™ Stapler with TRI-STAPLE™ Technology
Registration Number
NCT01241565
Lead Sponsor
Medtronic - MITG
Brief Summary

The objectives of this clinical trial are to compare the incidence and duration of air leaks and the incidence of prolonged air leaks (defined as \> 5 days by the Society for Thoracic Surgery) when using the ENDO GIA™ Stapler with ENDO GIA™ SULU with TRI-STAPLE™ Technology in a pulmonary resection via Video Assisted Thoracoscopic Surgery (VATS).

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
50
Inclusion Criteria
  • The subject must be 18 years of age or older.
  • The subject must be scheduled to undergo wedge resection or lobectomy via Video Assisted Thoracoscopic Surgery (VATS) for a lung nodule suspicious for or clinically proven to be primary lung cancer.
  • The subject must be able to tolerate general anesthesia and have cardiopulmonary reserve to tolerate the procedure.
  • The subject must be willing and able to comply with all study requirements and have understood and signed the informed consent.
Exclusion Criteria
  • The subject is pregnant or breastfeeding.
  • The subject is scheduled to undergo sleeve lobectomy, segmentectomy, bi-lobectomy, pneumonectomy or Lung Volume Reduction Surgery (LVRS), or lung biopsy for suspected interstitial lung disease.
  • A rib-spreading thoracotomy incision is scheduled to be performed, however the use of an access incision without rib-spreading for specimen removal or to facilitate hilar dissection is allowed. VATS procedures that are converted in the operating room to open procedures are not exclusionary.
  • The subject has received pre-operative chemotherapy or radiation therapy for the lung cancer that will be resected.
  • The subject is scheduled to receive intra-operative brachytherapy.
  • The subject has other severe illnesses that would preclude surgery such as unstable angina or myocardial infarction within 3 months.
  • Re-operative surgery is excluded if it is on the same side as the previous surgery.
  • Investigator determines that participation in the study may jeopardize the safety or welfare of the subject.
  • The subject is unable to comply with the follow-up visit schedule

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
ENDO GIA™ Stapler with TRI-STAPLE™ TechnologyENDO GIA™ Stapler with TRI-STAPLE™ TechnologySingle arm study, all patients will receive the study device.
Primary Outcome Measures
NameTimeMethod
Incidence of Prolonged Air LeaksDay 30

Defined as \> 5 days by the Society for Thoracic Surgery

Secondary Outcome Measures
NameTimeMethod
Duration of Chest Tube Following SurgeryApproximately Day 5

Chest tube duration was calculated as removal date - placement date + 1

Incidence of Serosal TearingDay 30
Incidence of Air LeaksDay 30

As recorded on the air leak log.

Duration of Air LeakDay 30

Measured in days. For patients discharged from the hospital with a Heimlich valve, the duration will be censored on the date of discharge.

Length of Hospital StayApproximately Day 6

Trial Locations

Locations (3)

Mayo Clinic

🇺🇸

Rochester, Minnesota, United States

Cedar Sinai Medical Center

🇺🇸

Los Angeles, California, United States

Advocate Christ Medical Center

🇺🇸

Oak Lawn, Illinois, United States

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