Treatment of Gingival Recession Using Mesenchymal Stem Cells
Phase 1
Completed
- Conditions
- Gingival Recession
- Interventions
- Other: standard treatmentBiological: mesenchymal stem cells
- Registration Number
- NCT04434794
- Brief Summary
Treatment of patients with gingival recession by injection of autologous adipose-derived mesenchymal stem cells mixed with collagen gel
- Detailed Description
Treatment of patients with gingival recession by injection of autologous adipose-derived mesenchymal stem cells mixed with collagen gel (1×106cells/0.2 ml). The volume of the mixture is divided into 4 equal injections in the gingival region of one tooth (one place injection volume is 0.05 ml of mixture).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 27
Inclusion Criteria
-gingival recession
Exclusion Criteria
- pregnancy
- breast-feeding
- acute and chronic infectious diseases: HIV, viral hepatitis, tuberculosis
- mental disorders
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description control standard treatment standard treatment according to clinical protocols mesenchymal stem cells mesenchymal stem cells standard treatment according to clinical protocols plus mesenchymal stem cells mesenchymal stem cells standard treatment standard treatment according to clinical protocols plus mesenchymal stem cells
- Primary Outcome Measures
Name Time Method number of patients cured 1 month number of patients cured
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
🇧🇾Minsk, Belarus