Heterogeneity of Tertiary Lymphoid Structures Predicts Distinct Malignancy and Immune Microenvironment in Prostate Cancer: a Retrospective Cohort Study
Completed
- Conditions
- Prostate Cancer
- Registration Number
- NCT06484127
- Lead Sponsor
- Fudan University
- Brief Summary
The aim of this study was to reveal the predictive value of spatial heterogeneity and maturity difference of tertiary lymphoid structure in pathological sections of prostate cancer patients for clinical features and prognosis. It provides a new idea for the selection of prostate cancer immunotherapy population in the future.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 200
Inclusion Criteria
1.patients diagnosed with prostate cancer who underwent radical prostatectomy or prostate puncture
Exclusion Criteria
- incomplete medical records, inadequate follow-up information, and confirmed non-prostatic acinar adenocarcinoma.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation between the detection of TLS(tertiary lymphoid structure) and clinical features 1 month
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Fudan University Shanghai Cancer Center
🇨🇳Shanghai, Shanghai, China