NCT00992355已完成不适用
Tobramycin 0.3% - Dexamethasone 0.1% Versus Tobramycin 0.3% - Dexamethasone 0.1% Plus Ketorolac Tromethamine 0.5% After Phacoemulsification Surgery. A Randomized Trial
Veroia General Hospital1 个研究点 分布在 1 个国家目标入组 97 人开始时间: 2009年1月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 97
- 试验地点
- 1
研究概览
简要总结
This randomized controlled trial compares two regimens of topical therapy:
- tobramycin 0.3% - dexamethasone 0.1% (TobraDex®, Alcon), one drop four times/day
- combination of tobramycin 0.3% - dexamethasone 0.1% (TobraDex®, Alcon), one drop four times/day, plus Ketorolac tromethamine 0.5% (Acular®, Allergan), one drop three times/day. The topical treatment is administered for 28 days after phacoemulsification.
Patients are independently assessed by two ophthalmologists. On day 28, patients are evaluated for
- corneal edema
- conjunctival redness
- anterior chamber reaction. Moreover, the cases necessitating continuation of treatment are compared in the two groups on day 28 and 42.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 55 Years 至 95 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Phacoemulsification (due to cataract)
- •Uneventful phacoemulsification surgery
排除标准
- •Disruption of the anterior lens capsule
- •Age-related macular degeneration
- •Proliferative diabetic retinopathy
研究组 & 干预措施
Tobramycin 0.3% - Dexamethasone 0.1%
Active Comparator
干预措施: Tobramycin 0.3% - Dexamethasone 0.1% (Drug)
Tobramycin-Dexamethasone plus Ketorolac tromethamine
Active Comparator
干预措施: Tobramycin 0.3% - Dexamethasone 0.1% plus Ketorolac tromethamine 0.5% (Drug)
研究者
研究点 (1)
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