Effect of Gum Chewing on Bowel Cleansing Before Colonoscopy

Phase 4

Completed

• Conditions: Bowel Preparation Scale; Adenoma Detection Rate
• Interventions: Dietary Supplement: gum+PEG; Drug: polyethylene glycol

• Registration Number: NCT02507037
• Lead Sponsor: Changhai Hospital

Brief Summary

In this randomized controlled study, consecutive outpatients scheduled for elective colonoscopy were randomized into two groups. Group A patients (n = 150) used 2 L PEG before colonoscopy. Patients in group B (n = 150) were additionally advised to chew sugarless gum plus 2 L PEG, The overall quality of colonoscopy cleaning was evaluated using the Boston Bowel Preparation Scale by endoscopists who was blinded to the intervention. Difficulty of procedure, patients' tolerance, and adverse events were also evaluated.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-07
• Study First Submitted: 2015-07-19
• Study First Submitted QC: 2015-07-22
• Study First Posted: 2015-07-23
• Primary Completion: 2015-08
• Study Completion: 2015-10
• Status Verified: 2016-03
• Last Update Submitted: 2016-03-17
• Last Update Posted: 2016-03-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• All adults (18-65) who were referred for outpatient colonoscopy.

Exclusion Criteria

• under 18 years or More than 65 years
• previous abdominal surgery
• major psychiatric disorders
• pregnancy
• presence of any contraindications for colonoscopy(eg, severe heart failure)
• recent inadequate colonoscopy history

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
gum+PEG	gum+PEG	used 2L PEG+sugarless gum
PEG	polyethylene glycol	only used 2L PEG

Primary Outcome Measures

Name	Time	Method
Boston Bowel Preparation Scale	2 days

Secondary Outcome Measures

Name	Time	Method
number of patient tolerability	2 days
Adenoma Detection Rate	2 days
number of patient willingness to repeat preparation	2 days