Trial Comparing Two Techniques of Celiac Plexus Neurolysis for Treatment of Pain in Carcinoma Pancreas

Phase 1

• Conditions: Pancreatic Cancer

• Registration Number: NCT01182831
• Lead Sponsor: Asian Institute of Gastroenterology, India

Brief Summary

Coeliac plexus neurolysis (CPN) is a management option for pain control in carcinoma pancreas.CPN is conventionally performed by percutaneous technique with fluoroscopic guidance. Endoscopic ultrasound (EUS) is increasingly used for CPN as it offers a better visualization of the plexus. There are limited data comparing the two modalities.The patients are on follow-up for 6 months post neurolysis.

Detailed Description

Carcinoma pancreas patients with abdominal pain requiring daily analgesics for more than 4 weeks were included.we are randomising about 100 patients into two groups to undergo either of the two procedures, i.e. celiac plexus neurolysis by percutaneous technique or by endoscopic ultrasound guided technique.The pain scores have been recorded by visual analogue scale for an average follow-up of 6 months.

Study Timeline

• Study Start: 2010-01
• Status Verified: 2010-08
• Study First Submitted: 2010-08-14
• Study First Submitted QC: 2010-08-16
• Study First Posted: 2010-08-17
• Last Update Submitted: 2010-08-27
• Last Update Posted: 2010-08-30
• Primary Completion: 2011-01
• Study Completion: 2011-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• all patients with carcinoma pancreas

Exclusion Criteria

• patients below 18 years of age and who have not given consent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
immediate pain relief	day of block to six months of follow-up

Trial Locations

Locations (1)

Asian Institute of Gastroenterology; 🇮🇳 Hyderabad, Andhra pradesh, India