Evaluating the effect of ethanol extract of propolis on palatal wound healing and complications after gingival graft surgery
Phase 3
Recruiting
- Conditions
- The wound of palate in patients who need gingival graft.
- Registration Number
- IRCT20240305061182N1
- Lead Sponsor
- Babol University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
patients over 18 years old
patients who need free gingival graft
The existence of sufficient dimensions of the free gingival graft donor site in the palate (length :10-15 mm, width :5-8 mm, thickness:1-1.5 mm)
Exclusion Criteria
Systemic diseases and conditions affecting wound healing (such as uncontrolled diabetes, autoimmune diseases, history of alcoholism)
Clinical attachment loss(greater than 3 mm) in the palatal site of premolars and maxillary first molars.
Use of corticosteroids
Use of antibiotics in the last month
Smoking
Allergy to amoxicillin-ibuprofen-chlorhexidine mouthwash
Allergy to bee products
Asthma
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Response to pain in patients after surgery. Timepoint: on days 3-7-14-21-42. Method of measurement: VAS (VISUAL ANALOGUE SCALE).;Response of patients to thermal stimuli after surgery. Timepoint: On days 3-7-14-21. Method of measurement: VAS (VISUAL ANALOGUE SCALE).;Complete epithelialization. Timepoint: on days 3-7-14-21-42. Method of measurement: Landry healing index.;Evaluating the degree of color matching, contour and distortion. Timepoint: on days 3-7-14-21-42. Method of measurement: Modified Manchester Scar Proforma index.
- Secondary Outcome Measures
Name Time Method