Health Behaviors and Time-of-Day: Older Adult Cognitive Function

Completed

• Conditions: Alteration of Cognitive Function; Ageing
• Interventions: Device: Polysomnograph; Device: Actiwatch

• Registration Number: NCT02300272
• Lead Sponsor: University of Florida

Brief Summary

This is a single-center, observational study design. Enrolled participants will be typically, healthy older adults. Participants will complete daily computerized measures, in addition to continuously wearing an Actiwatch device. The study period will last 2 weeks. The objectives of the study are to examine the impact of sleep, pain, and circadian rhythm on practice-related learning in older adults at their preferred versus nonpreferred times of day.

Detailed Description

Participants will be asked to review the informed consent and consent to the study prior to any study procedure.

There are four stages to this study: 1. a telephone interview, 2. an in-person interview and completion of questionnaires, 3. an in-home single night sleep recording, and 4. two weeks of computerized cognitive testing, subjective sleep and pain recordings, and wearing a Actiwatch.

During the telephone interview, participants will be asked question about their age, sleep, pain, and medical/mental health history. At a second visit, participants will complete a more in-depth interview of their physical health, mental health, sleep, and pain history. They will complete a brief test of their cognitive functioning. They will also complete 4 questionnaires about their time of day preference and mood. At the third visit, participants will visit the University of Florida to be connected to a machine which will monitor their sleep. Participants will return home to sleep while still connected to the machine and will return the machine to the University of Florida the next day. Participants will complete brief computerized daily questionnaires of sleep and pain and cognitive testing in the morning and evening, and and wear an actigraph (wristwatch-like device) that measures arm movements and ambient light for two weeks.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study First Submitted: 2014-11-20
• Study First Submitted QC: 2014-11-20
• Study First Posted: 2014-11-24
• Study Start: 2015-03
• Primary Completion: 2016-12
• Study Completion: 2016-12
• Status Verified: 2019-12
• Last Update Submitted: 2019-12-12
• Last Update Posted: 2019-12-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 88

Inclusion Criteria

• Age of 65 years and older
• Able to read and speak English
• Completion of Morningness-Eveningness Questionnaire

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Exclusion Criteria

• Significant medical or neurological disorder
• Major psychopathology
• Pain disorder other than fibromyalgia or osteoarthritis
• Sleep disorder other than insomnia
• Cognitive impairment
• Psychotropic or other medications known to alter sleep
• Unable to provide informed consent

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Typically healthy older adults	Polysomnograph	Adults 65 years and older with only common late-life medical conditions who will complete a screening that includes a Polysomnograph and assessment that includes Actiwatch.
Typically healthy older adults	Actiwatch	Adults 65 years and older with only common late-life medical conditions who will complete a screening that includes a Polysomnograph and assessment that includes Actiwatch.

Primary Outcome Measures

Name	Time	Method
Cognition as assessed by computerized neuropsychological testing	Morning and evening completion for 14 days	Cognitive domains include processing speed, immediate memory, delayed memory, and executive function

Trial Locations

Locations (1)

University of Florida; 🇺🇸 Gainesville, Florida, United States