Probiotic supplementation in multiple sclerosis
- Conditions
- Multiple Sclerosis.Multiple Sclerosis
- Registration Number
- IRCT20220713055465N2
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 90
Definitive diagnosis of multiple sclerosis based on 2017 MacDonald criteria
Relapsing Remitting MS (RRMS)
Informed consent to participate in the study
The presence of other neurological diseases at the same time as MS
Diabetes mellitus (DM)
Anemia
Other inflammatory diseases
Rheumatological diseases
Acute and chronic infectious diseases (including urinary tract infection)
Discopathy
Relapsing of the disease in the last 4 months
Receiving pulse coronet during the last 4 months
Progressive MS
CIS (Clinically isolated syndrome)
Literacy level below 12 years and lack of proficiency in Persian language
Severe depression and use of antidepressants
Alcohol or drug abuse
Thyroid disorders
Taking drugs that affect fatigue
Pregnancy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Oxidative stress markers including MDA? SOD? ATC? GSH? GPX1 ? GPX2. Timepoint: Baseline and end of treatment period. Method of measurement: Based on serum samples of the patients.
- Secondary Outcome Measures
Name Time Method