Correlations Between Fine Manual Motor Skills and Speech Articulation

Not Applicable

Not yet recruiting

• Conditions: Correlations Between Cerebral Motor Control During a Manual Task and During an Articulatory Task

• Registration Number: NCT06908863
• Lead Sponsor: Centre Hospitalier Universitaire de Nice

Brief Summary

The aim of this study is to examine the relationship between cerebral motor control during a manual task and during an articulary task, using functional MRI in a cohort or young adults aged between 18 and 35.

The literature reveals a well-established relationship between manual motor skills and speech from an anatomical and functional point of view. Some studies indicate a proximity between the motor cortical regions corresponding to the hand and the mouth, with a mutual interaction of the two functions from the earliest stages of life (for example, the Babkin reflex). Experimental data shows that hand movements can be influenced by mouth movements. Neurophysiological studies have demonstrated the existence of a link between these two systems in humans and monkeys.

To date, no study has identified the common cortical networks that are active during these two limb movements in a given sample of subjects. The aim of this study is to determine whether such networks exist. The results could be therapeutically relevant, particularly for stroke patients, by enabling more effective restoration of articulatory abilities through complementary limb movements.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-03-25
• Status Verified: 2025-04
• Study First Submitted QC: 2025-04-01
• Last Update Submitted: 2025-04-01
• Study First Posted: 2025-04-03
• Last Update Posted: 2025-04-03
• Study Start: 2025-05-01
• Primary Completion: 2026-01-01
• Study Completion: 2026-05-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Male or female between the ages of 18 and 35
2. Right-handed
3. Member of beneficiary of a social security insurance
4. Signature of an informed consent

Exclusion Criteria

1. Disorders of fine manual motor skills and/or articulatory disorders
2. A neurological history that has affected the subject's cerebral function (stroke, head injury)
3. Contraindication to MRI (presence of ferromagnetic material in the body, claustrophobia)
4. Pregnant women
5. Taking medication that may alter the cerebral haemodynamic signal

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Recording of brain activity during manual motor skills and speech articulation	2 weeks after inclusion	Detection and comparison of fMRI image sequences of brain areas based on variations in the difference between oxygenated and deoxygenated hemoglobin during manual motor tasks and silent phoneme articulation

Trial Locations

Locations (1)

CHU de Nice; 🇫🇷 Nice, Paca, France