Effect of carbon dioxide on depth of anesthesia in patients undergoing thyroidectomy.
Phase 1
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/11/060239
- Lead Sponsor
- Amrita institute of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA I or II patients, Patients undergoing thyroidectomy with incision approximately more than 10cm.
Exclusion Criteria
History of anesthetic allergy, History of chronic pain, Alcohol or drug abuse, Preoperative medication use that might influence sympathetic responses to surgical incision like betablockers
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method BIS indexTimepoint: At 1 minute after surgical incision
- Secondary Outcome Measures
Name Time Method 1.To study the effect of hypercarbia versus normocarbia on depth of anesthesia as reflected in BIS monitoring at MAC-bar concentration of sevoflurane at 1 minute min before and 5 minutes after surgical incision at same volatile anesthetic concentration during thyroidectomy surgeries.Timepoint: 1 minute before and 5 minutes after incision.;Correlation between arterial partial pressure of carbon dioxide (PaCO2) and end tidal carbon dioxide(ETCO2) at 5 minutes after surgical incision.Timepoint: At 5 minutes after surgical incision.;To compare the hemodynamic response between patients with hypercarbia and normocarbia at MAC-bar of sevoflurane to surgical incision.Timepoint: 1 minute before incision, 1 minute after incision and 5 minutes after incision.