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Clinical Trials/NCT05103085
NCT05103085
Unknown
Not Applicable

Screening for Hepatitis C Using a Rapid Diagnostic Orientation Test (TROD) in Patients Over 50 Years Old in the Digestive Endoscopy Department of the Europeen Hospital Marseille

Hôpital Européen Marseille1 site in 1 country5,000 target enrollmentJanuary 24, 2022
ConditionsHepatitis C

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hepatitis C
Sponsor
Hôpital Européen Marseille
Enrollment
5000
Locations
1
Primary Endpoint
Number of patients aged 50 and over tested positive for chronic viral hepatitis C during gastrointestinal endoscopy.
Last Updated
4 years ago

Overview

Brief Summary

Chronic viral hepatitis C is a public health problem and several management recommendations are available. According to the French High Authority of Health, hepatitis C screening consists of a targeted screening of people at risk of infection by the virus, in particular drug users, people from countries with a high prevalence of the virus or who have received care in those countries, people transfused before 1992, or people who are or have beenincarcerated .

French government recommendations aim to achieve elimination of hepatitis C virus HCV (as early as 2025) and since April 2018 the European Hospital Marseille is engaged in this battle and organizes every year "the day without hepatitis" in the hospital.

Since 2017, direct-acting antiviral treatments have become available in France to all patients infected with HCV, regardless of the degree of severity of their disease. These treatments are effective in more than 95% of cases and, in 2019, 18,000 people were cured. As of today, it is estimated that there are still 110,000 people likely to be treated in France. Among them, 75,000 are unaware of being HCV positive, people who need to be tested.

With one of the largest volumes of digestive endoscopic examinations in France, the European Hospital Marseille may be a significant source of screening for hepatitis C.

Our study proposes to evaluate hepatitis C screening in consenting patients hospitalized in the endoscopy department at the European Hospital Marseille.

Registry
clinicaltrials.gov
Start Date
January 24, 2022
End Date
September 2023
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Hôpital Européen Marseille
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Aged ≥ 50
  • Giving free and informed written consent
  • Being affiliated with or benefiting from a social security scheme

Exclusion Criteria

  • Patient unable to express consent

Outcomes

Primary Outcomes

Number of patients aged 50 and over tested positive for chronic viral hepatitis C during gastrointestinal endoscopy.

Time Frame: 16 months

Secondary Outcomes

  • Number of patients who refuse viral screening(16 months)
  • Investigation and identification of potential risk factors in patients diagnosed positive for chronic viral hepatitis C(16 months)
  • Number of viremic patients without risk factor(16 months)

Study Sites (1)

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