Brief Delay in Cord Clamping and Neurobehaviour in Preterms
- Conditions
- Preterm Birth
- Registration Number
- NCT01753843
- Lead Sponsor
- Lady Hardinge Medical College
- Brief Summary
RESEARCH HYPOTHESIS Brief delay(\>30 sec to \<60 sec ) in cord clamping as compared to early cord clamping (\< 20 sec) leads to a better short term neurobehavioural outcome in preterm (34-36 wks) neonates when assessed by neurobehavioral assessment of preterm infants (n.a.p.i.) at 37 weeks of post conceptional age
- Detailed Description
Delayed cord clamping (DCC) : Well described phenomenon in term infants .
* The optimal timing of clamping of umbilical cord in preterm infants : A subject of debate.
* Even a brief delay in cord clamping leads to an additional transfer of iron amounting to 40-50 mg/kg which may prevent iron deficiency.¹
* This low cost intervention can have significant public health importance in resource constrained settings.
* The effect of this intervention on neurobehaviour of preterm neonates has not been assessed.
* This aspect has been identified by WHO and Cochrane as a potentially researchable area
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 120
- All preterm deliveries -infants born at 34 weeks 0 days to 36 weeks +6 days gestational age as estimated by last menstrual period or early ultrasound scan.
- Infants delivered vaginally or by caesarean section in cephalic presentation
- Singleton pregnancy
- Parental consent
- Fetus with gross congenital anomaly
- Fetus with hydrops
- Rh negative pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method short term neurobehavioral outcome at 37 weeks post conceptional age using N.A.P.I (neurobehavioural assessment of preterm infant)
- Secondary Outcome Measures
Name Time Method measuring cord hematocrit at birth
Trial Locations
- Locations (1)
Lady Hardinge Medical College
🇮🇳New Delhi, Delhi, India
Lady Hardinge Medical College🇮🇳New Delhi, Delhi, India