Effect of Otamixaban Versus Unfractionated Heparin + Eptifibatide in Patients With Unstable Angina/Non ST Elevation Myocardial Infarction Undergoing Early Invasive Strategy
- Conditions
- Acute Coronary Syndrome
- Interventions
- Drug: OtamixabanDrug: Placebo (for Otamixaban)Drug: Placebo (for UFH)Drug: UFHDrug: Placebo (for Eptifibatide)Drug: Eptifibatide
- Registration Number
- NCT01076764
- Lead Sponsor
- Sanofi
- Brief Summary
Primary Objective:
* To demonstrate the superior efficacy (composite of all-cause death + Myocardial Infarction (MI)) of Otamixaban to Unfractionated Heparin (UFH) + Eptifibatide
Secondary Objectives:
* To demonstrate the superior efficacy (composite of all-cause death + MI + any stroke) of Otamixaban as compared to UFH + Eptifibatide
* To document the effect of Otamixaban on rehospitalization or prolongation of hospitalization due to a new episode of myocardial ischemia/myocardial infarction as compared to UFH + eptifibatide
* To document the effect on mortality (all cause death) of Otamixaban as compared to UFH + eptifibatide
* To document the safety of Otamixaban as compared to UFH + eptifibatide
* To document the effect of Otamixaban on thrombotic procedural complications during the index Percutaneous Coronary Intervention (PCI) as compared to UFH + eptifibatide
- Detailed Description
Up to the interim analysis, patients are randomized to one of the Otamixaban arms or the control arm (UFH + Eptifibatide). Then after interim analysis, patients will be randomized to the continued Otamixaban arm (per Data Monitoring Committee (DMC) decision based on interim analysis results) or the control arm (UFH + Eptifibatide). Except the DMC, all participants will remain blinded to this decision until the end of study.
The total duration of the study period per subject will range between 30 days and 180 days. Study end date being the Day 30 visit of the last randomized patient, follow up will be until Day 180 or study end date whichever comes first.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 13220
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Otamixaban - 0.080 mg/kg bolus + 0.100 mg/kg/h infusion Placebo (for UFH) From randomization until the end of the PCI or, if no PCI, up to Day 4 or hospital discharge whichever comes first: * Drug A: Otamixaban (0.080 mg/kg bolus followed by 0.100 mg/kg/h infusion) * Drug B: Placebo (for UFH) From PCI (downstream use) until 18-24 hour post PCI or hospital discharge whichever comes first: * Drug C: Placebo (for Eptifibatide) Otamixaban - 0.080 mg/kg bolus + 0.100 mg/kg/h infusion Placebo (for Eptifibatide) From randomization until the end of the PCI or, if no PCI, up to Day 4 or hospital discharge whichever comes first: * Drug A: Otamixaban (0.080 mg/kg bolus followed by 0.100 mg/kg/h infusion) * Drug B: Placebo (for UFH) From PCI (downstream use) until 18-24 hour post PCI or hospital discharge whichever comes first: * Drug C: Placebo (for Eptifibatide) Otamixaban - 0.080 mg/kg bolus + 0.140 mg/kg/h infusion Otamixaban From randomization until the end of the PCI or, if no PCI, up to Day 4 or hospital discharge whichever comes first: * Drug A: Otamixaban 0.080 mg/kg bolus followed by 0.140 mg/kg/h infusion) * Drug B: Placebo (for UFH) From PCI (downstream use) until 18-24 hour post PCI or hospital discharge whichever comes first: * Drug C: Placebo (for Eptifibatide) Otamixaban - 0.080 mg/kg bolus + 0.140 mg/kg/h infusion Placebo (for UFH) From randomization until the end of the PCI or, if no PCI, up to Day 4 or hospital discharge whichever comes first: * Drug A: Otamixaban 0.080 mg/kg bolus followed by 0.140 mg/kg/h infusion) * Drug B: Placebo (for UFH) From PCI (downstream use) until 18-24 hour post PCI or hospital discharge whichever comes first: * Drug C: Placebo (for Eptifibatide) Otamixaban - 0.080 mg/kg bolus + 0.140 mg/kg/h infusion Placebo (for Eptifibatide) From randomization until the end of the PCI or, if no PCI, up to Day 4 or hospital discharge whichever comes first: * Drug A: Otamixaban 0.080 mg/kg bolus followed by 0.140 mg/kg/h infusion) * Drug B: Placebo (for UFH) From PCI (downstream use) until 18-24 hour post PCI or hospital discharge whichever comes first: * Drug C: Placebo (for Eptifibatide) UFH + Eptifibatide UFH From randomization until the end of the PCI or, if no PCI, up to Day 4 or hospital discharge whichever comes first: * Drug A: Placebo (for Otamixaban) * Drug B: UFH (60 IU/kg bolus followed by 12 IU/kg/h infusion) From PCI (downstream use) until 18-24 hour post PCI or hospital discharge whichever comes first: * Drug C: Eptifibatide (180 mcg/kg bolus followed by 2 mcg/kg/min infusion) Otamixaban - 0.080 mg/kg bolus + 0.100 mg/kg/h infusion Otamixaban From randomization until the end of the PCI or, if no PCI, up to Day 4 or hospital discharge whichever comes first: * Drug A: Otamixaban (0.080 mg/kg bolus followed by 0.100 mg/kg/h infusion) * Drug B: Placebo (for UFH) From PCI (downstream use) until 18-24 hour post PCI or hospital discharge whichever comes first: * Drug C: Placebo (for Eptifibatide) UFH + Eptifibatide Placebo (for Otamixaban) From randomization until the end of the PCI or, if no PCI, up to Day 4 or hospital discharge whichever comes first: * Drug A: Placebo (for Otamixaban) * Drug B: UFH (60 IU/kg bolus followed by 12 IU/kg/h infusion) From PCI (downstream use) until 18-24 hour post PCI or hospital discharge whichever comes first: * Drug C: Eptifibatide (180 mcg/kg bolus followed by 2 mcg/kg/min infusion) UFH + Eptifibatide Eptifibatide From randomization until the end of the PCI or, if no PCI, up to Day 4 or hospital discharge whichever comes first: * Drug A: Placebo (for Otamixaban) * Drug B: UFH (60 IU/kg bolus followed by 12 IU/kg/h infusion) From PCI (downstream use) until 18-24 hour post PCI or hospital discharge whichever comes first: * Drug C: Eptifibatide (180 mcg/kg bolus followed by 2 mcg/kg/min infusion)
- Primary Outcome Measures
Name Time Method Efficacy: Adjudicated double composite of all-cause of death and new myocardial infarction from randomization (day 1) to day 7 Safety: Adjudicated Thrombolysis In Myocardial Infarction (TIMI) significant bleeding (composite of TIMI major and minor) from day 1 to day 7
- Secondary Outcome Measures
Name Time Method Adjudicated all-cause death from day 1 to day 30 Adjudicated Triple efficacy composite of all-cause death, new myocardial infarction and any stroke from day 1 to day 7 Rehospitalization or prolongation of hospitalization due to a new episode of myocardial ischemia/myocardial infarction from day 1 to day 30 Adjudicated Procedural thrombotic complications during the index PCI during index PCI
Trial Locations
- Locations (607)
Investigational Site Number 840911
🇺🇸Pittsburgh, Pennsylvania, United States
Investigational Site Number 032010
🇦🇷Cordoba, Argentina
Investigational Site Number 032020
🇦🇷Mendoza, Argentina
Investigational Site Number 032023
🇦🇷Resistencia, Argentina
Investigational Site Number 032002
🇦🇷Resistencia, Argentina
Investigational Site Number 032028
🇦🇷Rosario, Argentina
Investigational Site Number 032025
🇦🇷San Luis, Argentina
Investigational Site Number 032041
🇦🇷Santa Fe, Argentina
Investigational Site Number 032006
🇦🇷Santa Fe, Argentina
Investigational Site Number 040001
🇦🇹Wien, Austria
Investigational Site Number 112004
🇧🇾Gomel, Belarus
Investigational Site Number 112001
🇧🇾Minsk, Belarus
Investigational Site Number 056001
🇧🇪Bonheiden, Belgium
Investigational Site Number 724022
🇪🇸Barcelona, Spain
Investigational Site Number 056008
🇧🇪Leuven, Belgium
Investigational Site Number 100509
🇧🇬Ruse, Bulgaria
Investigational Site Number 100510
🇧🇬Sandanski, Bulgaria
Investigational Site Number 100502
🇧🇬Sofia, Bulgaria
Investigational Site Number 100507
🇧🇬Varna, Bulgaria
Investigational Site Number 100504
🇧🇬Veliko Tarnovo, Bulgaria
Investigational Site Number 100506
🇧🇬Yambol, Bulgaria
Investigational Site Number 152906
🇨🇱Concepcion, Chile
Investigational Site Number 152016
🇨🇱Valdivia, Chile
Investigational Site Number 152003
🇨🇱Antofagasta, Chile
Investigational Site Number 152010
🇨🇱Santiago, Chile
Investigational Site Number 203006
🇨🇿Zlin, Czech Republic
Investigational Site Number 818501
🇪🇬Cairo, Egypt
Investigational Site Number 818503
🇪🇬Giza, Egypt
Investigational Site Number 818502
🇪🇬Cairo, Egypt
Investigational Site Number 300003
🇬🇷Melissia, Greece
Investigational Site Number 356032
🇮🇳Mumbai, India
Investigational Site Number 300006
🇬🇷Thessaloniki, Greece
Investigational Site Number 356035
🇮🇳Nagpur, India
Investigational Site Number 356026
🇮🇳New Delhi, India
Investigational Site Number 376007
🇮🇱Safed, Israel
Investigational Site Number 376009
🇮🇱Haifa, Israel
Investigational Site Number 376010
🇮🇱Holon, Israel
Investigational Site Number 376002
🇮🇱Jerusalem, Israel
Investigational Site Number 376012
🇮🇱Tzrifin, Israel
Investigational Site Number 484019
🇲🇽Merida, Mexico
Investigational Site Number 578903
🇳🇴Arendal, Norway
Investigational Site Number 591502
🇵🇦Panamá, Panama
Investigational Site Number 604017
🇵🇪Lima, Peru
Investigational Site Number 616046
🇵🇱Katowice, Poland
Investigational Site Number 616003
🇵🇱Radom, Poland
Investigational Site Number 616034
🇵🇱Klodzko, Poland
Investigational Site Number 616045
🇵🇱Krakow, Poland
Investigational Site Number 616002
🇵🇱Krakow, Poland
Investigational Site Number 616018
🇵🇱Walbrzych, Poland
Investigational Site Number 616014
🇵🇱Warszawa, Poland
Investigational Site Number 616001
🇵🇱Warszawa, Poland
Investigational Site Number 620010
🇵🇹Almada, Portugal
Investigational Site Number 620001
🇵🇹Coimbra, Portugal
Investigational Site Number 642001
🇷🇴Bucuresti, Romania
Investigational Site Number 642005
🇷🇴Cluj Napoca, Romania
Investigational Site Number 616029
🇵🇱Lodz, Poland
Investigational Site Number 616004
🇵🇱Lomza, Poland
Investigational Site Number 616024
🇵🇱Lubin, Poland
Investigational Site Number 840527
🇺🇸Tupelo, Mississippi, United States
Investigational Site Number 840902
🇺🇸St. Petersburg, Florida, United States
Investigational Site Number 616041
🇵🇱Lublin, Poland
Investigational Site Number 616020
🇵🇱Zamosc, Poland
Investigational Site Number 620003
🇵🇹Lisboa, Portugal
Investigational Site Number 620002
🇵🇹Coimbra, Portugal
Investigational Site Number 642004
🇷🇴Bucuresti, Romania
Investigational Site Number 643018
🇷🇺Barnaul, Russian Federation
Investigational Site Number 643015
🇷🇺Ekaterinburg, Russian Federation
Investigational Site Number 688502
🇷🇸Sremska Kamenica, Serbia
Investigational Site Number 703002
🇸🇰Martin, Slovakia
Investigational Site Number 703001
🇸🇰Nitra, Slovakia
Investigational Site Number 688504
🇷🇸Zemun, Serbia
Investigational Site Number 158008
🇨🇳Taichung, Taiwan
Investigational Site Number 764005
🇹🇭Bangkok, Thailand
Investigational Site Number 764006
🇹🇭Rajathavee, Thailand
Investigational Site Number 158904
🇨🇳Taipei, Taiwan
Investigational Site Number 764903
🇹🇭Muang, Thailand
Investigational Site Number 788006
🇹🇳Monastir, Tunisia
Investigational Site Number 788005
🇹🇳Monastir, Tunisia
Investigational Site Number 788004
🇹🇳Tunis, Tunisia
Investigational Site Number 804004
🇺🇦Cherkasy, Ukraine
Investigational Site Number 704006
🇻🇳Hanoi, Vietnam
Investigational Site Number 804003
🇺🇦Zaporozhie, Ukraine
Investigational Site Number 356010
🇮🇳Pune, India
Investigational Site Number 840207
🇺🇸Houston, Texas, United States
Investigational Site Number 840559
🇺🇸Houston, Texas, United States
Investigational Site Number 840586
🇺🇸Houston, Texas, United States
Investigational Site Number 840510
🇺🇸Minneapolis, Minnesota, United States
Investigational Site Number 840525
🇺🇸Minneapolis, Minnesota, United States
Investigational Site Number 764007
🇹🇭Klong Luang, Thailand
Investigational Site Number 840569
🇺🇸Phoenix, Arizona, United States
Investigational Site Number 840703
🇺🇸Phoenix, Arizona, United States
Investigational Site Number 840065
🇺🇸San Francisco, California, United States
Investigational Site Number 840049
🇺🇸Oklahoma City, Oklahoma, United States
Investigational Site Number 840905
🇺🇸Oklahoma City, Oklahoma, United States
Investigational Site Number 840047
🇺🇸Lake Mary, Florida, United States
Investigational Site Number 840009
🇺🇸Ocala, Florida, United States
Investigational Site Number 840706
🇺🇸Miami, Florida, United States
Investigational Site Number 840028
🇺🇸Jacksonville, Florida, United States
Investigational Site Number 840557
🇺🇸Los Angeles, California, United States
Investigational Site Number 840560
🇺🇸Muncie, Indiana, United States
Investigational Site Number 840904
🇺🇸Ames, Iowa, United States
Investigational Site Number 840912
🇺🇸Overland, Kansas, United States
Investigational Site Number 840071
🇺🇸Los Angeles, California, United States
Investigational Site Number 840101
🇺🇸Anaheim, California, United States
Investigational Site Number 840015
🇺🇸Huntsville, Alabama, United States
Investigational Site Number 840213
🇺🇸Beverley Hills, California, United States
Investigational Site Number 840151
🇺🇸Anaheim, California, United States
Investigational Site Number 840572
🇺🇸Huntington Beach, California, United States
Investigational Site Number 840551
🇺🇸Bridgeport, Connecticut, United States
Investigational Site Number 840561
🇺🇸Santa Rosa, California, United States
Investigational Site Number 840531
🇺🇸Saginaw, Michigan, United States
Investigational Site Number 840554
🇺🇸Indianapolis, Indiana, United States
Investigational Site Number 840146
🇺🇸Ocala, Florida, United States
Investigational Site Number 840209
🇺🇸Independence, Missouri, United States
Investigational Site Number 840517
🇺🇸Dearborn, Michigan, United States
Investigational Site Number 840042
🇺🇸Hammond, Indiana, United States
Investigational Site Number 840058
🇺🇸West Des Moines, Iowa, United States
Investigational Site Number 840719
🇺🇸Gainesville, Georgia, United States
Investigational Site Number 840190
🇺🇸Chicago, Illinois, United States
Investigational Site Number 840208
🇺🇸Bridgeton, Missouri, United States
Investigational Site Number 840530
🇺🇸St Louis, Missouri, United States
Investigational Site Number 840580
🇺🇸St Louis, Missouri, United States
Investigational Site Number 840585
🇺🇸Charlotte, North Carolina, United States
Investigational Site Number 840518
🇺🇸Brooklyn, New York, United States
Investigational Site Number 840136
🇺🇸Minot, North Dakota, United States
Investigational Site Number 840206
🇺🇸Eugene, Oregon, United States
Investigational Site Number 840082
🇺🇸Toledo, Ohio, United States
Investigational Site Number 840003
🇺🇸Erie, Pennsylvania, United States
Investigational Site Number 840025
🇺🇸Midwest City, Oklahoma, United States
Investigational Site Number 840098
🇺🇸Harrisburg, Pennsylvania, United States
Investigational Site Number 840573
🇺🇸Philadelphia, Pennsylvania, United States
Investigational Site Number 840901
🇺🇸Tulsa, Oklahoma, United States
Investigational Site Number 840060
🇺🇸Dallas, Texas, United States
Investigational Site Number 840023
🇺🇸Amarillo, Texas, United States
Investigational Site Number 840578
🇺🇸Dallas, Texas, United States
Investigational Site Number 840090
🇺🇸Houston, Texas, United States
Investigational Site Number 032014
🇦🇷Caba, Argentina
Investigational Site Number 840555
🇺🇸Wichita Falls, Texas, United States
Investigational Site Number 840087
🇺🇸Tyler, Texas, United States
Investigational Site Number 032039
🇦🇷Capital Federal, Argentina
Investigational Site Number 032045
🇦🇷Capital Federal, Argentina
Investigational Site Number 032029
🇦🇷Ciudad Autonoma De Bs.As, Argentina
Investigational Site Number 840165
🇺🇸Salem, Virginia, United States
Investigational Site Number 032003
🇦🇷Buenos Aires, Argentina
Investigational Site Number 840565
🇺🇸Winchester, Virginia, United States
Investigational Site Number 032043
🇦🇷Buenos Aires, Argentina
Investigational Site Number 032007
🇦🇷Capital Federal, Argentina
Investigational Site Number 032004
🇦🇷Rosario, Argentina
Investigational Site Number 032036
🇦🇷Ciudad De Buenos Aires, Argentina
Investigational Site Number 032044
🇦🇷Cordoba, Argentina
Investigational Site Number 032001
🇦🇷Corrientes, Argentina
Investigational Site Number 032035
🇦🇷Florencio Varela, Argentina
Investigational Site Number 032018
🇦🇷La Plata, Argentina
Investigational Site Number 032022
🇦🇷Pilar, Argentina
Investigational Site Number 036001
🇦🇺Herston, Australia
Investigational Site Number 032008
🇦🇷San Miguel De Tucuman, Argentina
Investigational Site Number 112003
🇧🇾Minsk, Belarus
Investigational Site Number 100508
🇧🇬Kazanlak, Bulgaria
Investigational Site Number 076013
🇧🇷Passo Fundo, Brazil
Investigational Site Number 036003
🇦🇺Prahran, Australia
Investigational Site Number 036008
🇦🇺Adelaide, Australia
Investigational Site Number 036913
🇦🇺Hobart, Australia
Investigational Site Number 036011
🇦🇺Liverpool, Australia
Investigational Site Number 036004
🇦🇺Ballarat, Australia
Investigational Site Number 040002
🇦🇹Wien, Austria
Investigational Site Number 076016
🇧🇷Maringa, Brazil
Investigational Site Number 036010
🇦🇺Concord, Australia
Investigational Site Number 112002
🇧🇾Minsk, Belarus
Investigational Site Number 076025
🇧🇷Campinas, Brazil
Investigational Site Number 056007
🇧🇪Brugge, Belgium
Investigational Site Number 056003
🇧🇪Brussels, Belgium
Investigational Site Number 100505
🇧🇬Pleven, Bulgaria
Investigational Site Number 124005
🇨🇦Gatineau, Canada
Investigational Site Number 124004
🇨🇦Montreal, Canada
Investigational Site Number 152005
🇨🇱Iquique, Chile
Investigational Site Number 152902
🇨🇱Santiago, Chile
Investigational Site Number 124007
🇨🇦Sherbrooke, Canada
Investigational Site Number 124009
🇨🇦St. John, Canada
Investigational Site Number 152012
🇨🇱Santiago, Chile
Investigational Site Number 170002
🇨🇴Bucaramanga, Colombia
Investigational Site Number 152912
🇨🇱Valparaíso, Chile
Investigational Site Number 152910
🇨🇱Viña Del Mar, Chile
Investigational Site Number 170016
🇨🇴Barranquilla, Colombia
Investigational Site Number 191503
🇭🇷Zagreb, Croatia
Investigational Site Number 191506
🇭🇷Zagreb, Croatia
Investigational Site Number 191505
🇭🇷Zagreb, Croatia
Investigational Site Number 818504
🇪🇬Cairo, Egypt
Investigational Site Number 233001
🇪🇪Tallinn, Estonia
Investigational Site Number 250010
🇫🇷Bayonne, France
Investigational Site Number 233901
🇪🇪Tallinn, Estonia
Investigational Site Number 250003
🇫🇷Dijon Cedex, France
Investigational Site Number 250015
🇫🇷Mulhouse, France
Investigational Site Number 276022
🇩🇪Berlin, Germany
Investigational Site Number 250013
🇫🇷Le Chesnay Cedex, France
Investigational Site Number 250009
🇫🇷Paris, France
Investigational Site Number 276024
🇩🇪Berlin, Germany
Investigational Site Number 250007
🇫🇷Rouen, France
Investigational Site Number 276004
🇩🇪Berlin, Germany
Investigational Site Number 276023
🇩🇪Bonn, Germany
Investigational Site Number 276901
🇩🇪Freiburg, Germany
Investigational Site Number 276003
🇩🇪Hamburg, Germany
Investigational Site Number 276904
🇩🇪Heidenheim, Germany
Investigational Site Number 276009
🇩🇪Heidelberg, Germany
Investigational Site Number 276005
🇩🇪München, Germany
Investigational Site Number 276905
🇩🇪Mönchengladbach, Germany
Investigational Site Number 300009
🇬🇷Alexandroupolis, Greece
Investigational Site Number 300004
🇬🇷Athens, Greece
Investigational Site Number 300007
🇬🇷Chios, Greece
Investigational Site Number 348005
🇭🇺Szombathely, Hungary
Investigational Site Number 348008
🇭🇺Budapest, Hungary
Investigational Site Number 356019
🇮🇳Ahmedabad, India
Investigational Site Number 356004
🇮🇳Ahmedabad, India
Investigational Site Number 356040
🇮🇳Hyderabad, India
Investigational Site Number 356014
🇮🇳Jaipur, India
Investigational Site Number 356039
🇮🇳Madurai, India
Investigational Site Number 356003
🇮🇳Karamsad, India
Investigational Site Number 356031
🇮🇳Mumbai, India
Investigational Site Number 356036
🇮🇳Nashik, India
Investigational Site Number 376008
🇮🇱Tel Aviv, Israel
Investigational Site Number 376001
🇮🇱Tel Hashomer, Israel
Investigational Site Number 380902
🇮🇹Bergamo, Italy
Investigational Site Number 360505
🇮🇩Bandung, Indonesia
Investigational Site Number 410004
🇰🇷Goyang, Korea, Republic of
Investigational Site Number 360503
🇮🇩Jakarta, Indonesia
Investigational Site Number 380929
🇮🇹Castellanza, Italy
Investigational Site Number 380918
🇮🇹Bologna, Italy
Investigational Site Number 376003
🇮🇱Ashkelon, Israel
Investigational Site Number 380926
🇮🇹Conegliano, Italy
Investigational Site Number 360502
🇮🇩Jakarta, Indonesia
Investigational Site Number 380933
🇮🇹Messina, Italy
Investigational Site Number 380927
🇮🇹Rovigo, Italy
Investigational Site Number 400501
🇯🇴Amman, Jordan
Investigational Site Number 428001
🇱🇻Riga, Latvia
Investigational Site Number 440003
🇱🇹Kaunas, Lithuania
Investigational Site Number 410014
🇰🇷Daegu, Korea, Republic of
Investigational Site Number 400502
🇯🇴Irbid, Jordan
Investigational Site Number 410018
🇰🇷Guri, Korea, Republic of
Investigational Site Number 410005
🇰🇷Busan, Korea, Republic of
Investigational Site Number 410006
🇰🇷Busan, Korea, Republic of
Investigational Site Number 410007
🇰🇷Seongnam, Korea, Republic of
Investigational Site Number 410012
🇰🇷Seoul, Korea, Republic of
Investigational Site Number 410016
🇰🇷Gwangju, Korea, Republic of
Investigational Site Number 528003
🇳🇱Alkmaar, Netherlands
Investigational Site Number 604005
🇵🇪Lambayeque, Peru
Investigational Site Number 458001
🇲🇾Kuching, Malaysia
Investigational Site Number 484911
🇲🇽San Luis Potosi, Mexico
Investigational Site Number 554004
🇳🇿Auckland, New Zealand
Investigational Site Number 410008
🇰🇷Seoul, Korea, Republic of
Investigational Site Number 410001
🇰🇷Seoul, Korea, Republic of
Investigational Site Number 428002
🇱🇻Liepaja, Latvia
Investigational Site Number 428003
🇱🇻Riga, Latvia
Investigational Site Number 807501
🇲🇰Skopje, Macedonia, The Former Yugoslav Republic of
Investigational Site Number 428004
🇱🇻Daugavpils, Latvia
Investigational Site Number 410003
🇰🇷Seoul, Korea, Republic of
Investigational Site Number 410015
🇰🇷Wonju, Korea, Republic of
Investigational Site Number 410013
🇰🇷Suwon, Korea, Republic of
Investigational Site Number 422502
🇱🇧Beirut, Lebanon
Investigational Site Number 422505
🇱🇧Beirut, Lebanon
Investigational Site Number 440001
🇱🇹Siauliai, Lithuania
Investigational Site Number 484907
🇲🇽Aguascalientes, Mexico
Investigational Site Number 484902
🇲🇽Guadalajara, Mexico
Investigational Site Number 484004
🇲🇽Monterrey, Mexico
Investigational Site Number 484015
🇲🇽Guadalajara, Mexico
Investigational Site Number 484003
🇲🇽Mexico City, Mexico
Investigational Site Number 484020
🇲🇽Puebla, Mexico
Investigational Site Number 484009
🇲🇽Aguascalientes, Mexico
Investigational Site Number 484901
🇲🇽Guadalajara, Mexico
Investigational Site Number 484910
🇲🇽Morelia, Michoacan, Mexico
Investigational Site Number 484012
🇲🇽San Luis Potosi, Mexico
Investigational Site Number 484013
🇲🇽Xalapa, Mexico
Investigational Site Number 484914
🇲🇽México Df, Mexico
Investigational Site Number 484017
🇲🇽Queretaro, Mexico
Investigational Site Number 499501
🇲🇪Podgorica, Montenegro
Investigational Site Number 554002
🇳🇿Nelson, New Zealand
Investigational Site Number 528005
🇳🇱Arnhem, Netherlands
Investigational Site Number 528007
🇳🇱Leeuwarden, Netherlands
Investigational Site Number 578901
🇳🇴Bergen, Norway
Investigational Site Number 604012
🇵🇪Lima, Peru
Investigational Site Number 528004
🇳🇱Nieuwegein, Netherlands
Investigational Site Number 528002
🇳🇱Rotterdam, Netherlands
Investigational Site Number 554001
🇳🇿Hamilton, New Zealand
Investigational Site Number 578902
🇳🇴Stavanger, Norway
Investigational Site Number 604006
🇵🇪Lima, Peru
Investigational Site Number 616038
🇵🇱Bialystok, Poland
Investigational Site Number 616009
🇵🇱Bytom, Poland
Investigational Site Number 591504
🇵🇦Panama, Panama
Investigational Site Number 604003
🇵🇪Lima, Peru
Investigational Site Number 604008
🇵🇪Lima, Peru
Investigational Site Number 616032
🇵🇱Jelenia Gora, Poland
Investigational Site Number 616017
🇵🇱Bydgoszcz, Poland
Investigational Site Number 616027
🇵🇱Elk, Poland
Investigational Site Number 616022
🇵🇱Torun, Poland
Investigational Site Number 616019
🇵🇱Tarnów, Poland
Investigational Site Number 620015
🇵🇹Ponta Delgada, Portugal
Investigational Site Number 620004
🇵🇹Setúbal, Portugal
Investigational Site Number 620011
🇵🇹Évora, Portugal
Investigational Site Number 642003
🇷🇴Targu-Mures, Romania
Investigational Site Number 643004
🇷🇺Moscow, Russian Federation
Investigational Site Number 643003
🇷🇺Moscow, Russian Federation
Investigational Site Number 643016
🇷🇺Nizniy Novgorod, Russian Federation
Investigational Site Number 643020
🇷🇺Moscow, Russian Federation
Investigational Site Number 643001
🇷🇺Moscow, Russian Federation
Investigational Site Number 643008
🇷🇺Saint-Peterburg, Russian Federation
Investigational Site Number 710001
🇿🇦Cape Town, South Africa
Investigational Site Number 643019
🇷🇺Saint-Petersburg, Russian Federation
Investigational Site Number 643007
🇷🇺St-Petersburg, Russian Federation
Investigational Site Number 703003
🇸🇰Banska Bystrica, Slovakia
Investigational Site Number 643012
🇷🇺Tomsk, Russian Federation
Investigational Site Number 643017
🇷🇺Yaroslavl, Russian Federation
Investigational Site Number 702002
🇸🇬Singapore, Singapore
Investigational Site Number 688501
🇷🇸Kragujevac, Serbia
Investigational Site Number 688503
🇷🇸Nis, Serbia
Investigational Site Number 688506
🇷🇸Zemun, Serbia
Investigational Site Number 702001
🇸🇬Singapore, Singapore
Investigational Site Number 724021
🇪🇸Barcelona, Spain
Investigational Site Number 724002
🇪🇸Barcelona, Spain
Investigational Site Number 724013
🇪🇸Alcorcón, Spain
Investigational Site Number 724016
🇪🇸Galdakao, Spain
Investigational Site Number 756002
🇨🇭Zürich, Switzerland
Investigational Site Number 756001
🇨🇭Lugano, Switzerland
Investigational Site Number 724027
🇪🇸Madrid, Spain
Investigational Site Number 724003
🇪🇸Madrid, Spain
Investigational Site Number 724023
🇪🇸Girona, Spain
Investigational Site Number 724902
🇪🇸Madrid, Spain
Investigational Site Number 724026
🇪🇸Elche, Spain
Investigational Site Number 158003
🇨🇳Linkou, Taiwan
Investigational Site Number 724006
🇪🇸La Laguna, Spain
Investigational Site Number 724012
🇪🇸Santiago De Compostela, Spain
Investigational Site Number 792010
🇹🇷Adana, Turkey
Investigational Site Number 724010
🇪🇸Torrevieja, Spain
Investigational Site Number 724024
🇪🇸Valencia, Spain
Investigational Site Number 158007
🇨🇳Kaohsiung, Taiwan
Investigational Site Number 158002
🇨🇳Kaohsiung, Taiwan
Investigational Site Number 764002
🇹🇭Bangkok, Thailand
Investigational Site Number 764004
🇹🇭Khon Kaen, Thailand
Investigational Site Number 788002
🇹🇳Ariana, Tunisia
Investigational Site Number 792023
🇹🇷Ankara, Turkey
Investigational Site Number 792009
🇹🇷Antalya, Turkey
Investigational Site Number 792006
🇹🇷Erzurum, Turkey
Investigational Site Number 158001
🇨🇳Taipei, Taiwan
Investigational Site Number 764901
🇹🇭Bangkok, Thailand
Investigational Site Number 158009
🇨🇳Taipei, Taiwan
Investigational Site Number 792022
🇹🇷Bursa, Turkey
Investigational Site Number 792008
🇹🇷Bursa, Turkey
Investigational Site Number 792020
🇹🇷Eskisehir, Turkey
Investigational Site Number 792011
🇹🇷Izmir, Turkey
Investigational Site Number 704003
🇻🇳Ho Chi Minh City, Vietnam
Investigational Site Number 792001
🇹🇷Izmir, Turkey
Investigational Site Number 792021
🇹🇷Samsun, Turkey
Investigational Site Number 792019
🇹🇷Mersin, Turkey
Investigational Site Number 792026
🇹🇷Sivas, Turkey
Investigational Site Number 826008
🇬🇧Bournemouth, United Kingdom
Investigational Site Number 792003
🇹🇷Izmir, Turkey
Investigational Site Number 792014
🇹🇷Kocaeli, Turkey
Investigational Site Number 792012
🇹🇷Kayseri, Turkey
Investigational Site Number 804001
🇺🇦Kharkiv, Ukraine
Investigational Site Number 792025
🇹🇷Malatya, Turkey
Investigational Site Number 804005
🇺🇦Lviv, Ukraine
Investigational Site Number 704001
🇻🇳Ho Chi Minh City, Vietnam
Investigational Site Number 380904
🇮🇹Brescia, Italy
Investigational Site Number 380928
🇮🇹Brescia, Italy
Investigational Site Number 380930
🇮🇹Catania, Italy
Investigational Site Number 380912
🇮🇹Catania, Italy
Investigational Site Number 380932
🇮🇹Cittadella, Italy
Investigational Site Number 380909
🇮🇹Empoli, Italy
Investigational Site Number 380923
🇮🇹Massa, Italy
Investigational Site Number 380935
🇮🇹Massa, Italy
Investigational Site Number 380924
🇮🇹Forlì, Italy
Investigational Site Number 380908
🇮🇹Livorno, Italy
Investigational Site Number 380910
🇮🇹Milano, Italy
Investigational Site Number 380905
🇮🇹Modena, Italy
Investigational Site Number 380936
🇮🇹Napoli, Italy
Investigational Site Number 380901
🇮🇹Perugia, Italy
Investigational Site Number 380919
🇮🇹Pordenone, Italy
Investigational Site Number 380921
🇮🇹Rozzano, Italy
Investigational Site Number 380931
🇮🇹Roma, Italy
Investigational Site Number 380916
🇮🇹Reggio Emilia, Italy
Investigational Site Number 380925
🇮🇹Treviso, Italy
Investigational Site Number 792030
🇹🇷Edirne, Turkey
Investigational Site Number 792018
🇹🇷Istanbul, Turkey
Investigational Site Number 792032
🇹🇷Istanbul, Turkey
Investigational Site Number 792028
🇹🇷Istanbul, Turkey
Investigational Site Number 792016
🇹🇷Istanbul, Turkey
Investigational Site Number 792029
🇹🇷Istanbul, Turkey
Investigational Site Number 792015
🇹🇷Konya, Turkey
Investigational Site Number 826007
🇬🇧Bradford, United Kingdom
Investigational Site Number 826001
🇬🇧Craigavon, United Kingdom
Investigational Site Number 826005
🇬🇧East Kilbride, United Kingdom
Investigational Site Number 826002
🇬🇧Hull, United Kingdom
Investigational Site Number 826006
🇬🇧Manchester, United Kingdom
Investigational Site Number 826003
🇬🇧St Leonards, United Kingdom
Investigational Site Number 076007
🇧🇷Sao Paulo, Brazil
Investigational Site Number 076022
🇧🇷Porto Alegre, Brazil
Investigational Site Number 076015
🇧🇷Marilia, Brazil
Investigational Site Number 076011
🇧🇷Fortaleza, Brazil
Investigational Site Number 076009
🇧🇷Porto Alegre, Brazil
Investigational Site Number 076001
🇧🇷Porto Alegre, Brazil
Investigational Site Number 076014
🇧🇷Sao Jose Do Rio Preto, Brazil
Investigational Site Number 076012
🇧🇷Sao Paulo, Brazil
Investigational Site Number 076020
🇧🇷Sao Paulo, Brazil
Investigational Site Number 076027
🇧🇷Rio De Janeiro, Brazil
Investigational Site Number 076029
🇧🇷Salvador, Brazil
Investigational Site Number 076008
🇧🇷Uberlandia, Brazil
Investigational Site Number 076024
🇧🇷Votuporanga, Brazil
Investigational Site Number 410017
🇰🇷Daejeon, Korea, Republic of
Investigational Site Number 410011
🇰🇷Seoul, Korea, Republic of
Investigational Site Number 410009
🇰🇷Seoul, Korea, Republic of
Investigational Site Number 410010
🇰🇷Seoul, Korea, Republic of
Investigational Site Number 276002
🇩🇪Kassel, Germany
Investigational Site Number 840210
🇺🇸St. Louis, Missouri, United States
Investigational Site Number 724007
🇪🇸Cáceres, Spain
Investigational Site Number 724901
🇪🇸Barcelona, Spain
Investigational Site Number 724904
🇪🇸Murcia, Spain
Investigational Site Number 724017
🇪🇸Málaga, Spain
Investigational Site Number 724005
🇪🇸Santander, Spain
Investigational Site Number 724903
🇪🇸Terrassa, Spain
Investigational Site Number 840193
🇺🇸Oklahoma City, Oklahoma, United States
Investigational Site Number 840201
🇺🇸Long Beach, California, United States
Investigational Site Number 840185
🇺🇸Fort Lauderdale, Florida, United States
Investigational Site Number 840500
🇺🇸Melbourne, Florida, United States
Investigational Site Number 840105
🇺🇸Aurora, Illinois, United States
Investigational Site Number 380917
🇮🇹Roma, Italy
Investigational Site Number 724018
🇪🇸San Juan De Alicante, Spain
Investigational Site Number 840052
🇺🇸St. Louis, Missouri, United States
Investigational Site Number 076023
🇧🇷Recife, Brazil
Investigational Site Number 840205
🇺🇸Chicago, Illinois, United States
Investigational Site Number 076030
🇧🇷Recife, Brazil
Investigational Site Number 840532
🇺🇸Boise, Idaho, United States
Investigational Site Number 840515
🇺🇸Greenville, North Carolina, United States
Investigational Site Number 840903
🇺🇸Northridge, California, United States
Investigational Site Number 840721
🇺🇸Littleton, Colorado, United States
Investigational Site Number 840148
🇺🇸Joliet, Illinois, United States
Investigational Site Number 840021
🇺🇸Sarasota, Florida, United States
Investigational Site Number 840521
🇺🇸Harvey, Illinois, United States
Investigational Site Number 840544
🇺🇸Kalamazoo, Michigan, United States
Investigational Site Number 840564
🇺🇸Lake Charles, Louisiana, United States
Investigational Site Number 840534
🇺🇸Alexandria, Louisiana, United States
Investigational Site Number 840529
🇺🇸Kalispell, Montana, United States
Investigational Site Number 840157
🇺🇸Reno, Nevada, United States
Investigational Site Number 840566
🇺🇸Raleigh, North Carolina, United States
Investigational Site Number 840539
🇺🇸New York, New York, United States
Investigational Site Number 840908
🇺🇸Winston Salem, North Carolina, United States
Investigational Site Number 840540
🇺🇸Chambersburg, Pennsylvania, United States
Investigational Site Number 840519
🇺🇸Doylestown, Pennsylvania, United States
Investigational Site Number 840075
🇺🇸Pittsburgh, Pennsylvania, United States
Investigational Site Number 840072
🇺🇸Oak Ridge, Tennessee, United States
Investigational Site Number 840211
🇺🇸Washington, Pennsylvania, United States
Investigational Site Number 840715
🇺🇸Fort Worth, Texas, United States
Investigational Site Number 840910
🇺🇸Victoria, Texas, United States
Investigational Site Number 840513
🇺🇸Manitowoc, Wisconsin, United States
Investigational Site Number 032046
🇦🇷Buenos Aires, Argentina
Investigational Site Number 840121
🇺🇸Tacoma, Washington, United States
Investigational Site Number 032013
🇦🇷Avellaneda, Argentina
Investigational Site Number 032048
🇦🇷Adrogue, Argentina
Investigational Site Number 032027
🇦🇷La Plata, Argentina
Investigational Site Number 032033
🇦🇷Olivos, Argentina
Investigational Site Number 032021
🇦🇷Rosario, Argentina
Investigational Site Number 032005
🇦🇷Rosario, Argentina
Investigational Site Number 032040
🇦🇷Rosario, Argentina
Investigational Site Number 032024
🇦🇷San Martin, Argentina
Investigational Site Number 056006
🇧🇪Haine-Saint-Paul, Belgium
Investigational Site Number 076002
🇧🇷Sao Jose Do Rio Preto, Brazil
Investigational Site Number 076004
🇧🇷Porto Alegre, Brazil
Investigational Site Number 100503
🇧🇬Sofia, Bulgaria
Investigational Site Number 100511
🇧🇬Blagoevgrad, Bulgaria
Investigational Site Number 124006
🇨🇦Hamilton, Canada
Investigational Site Number 124001
🇨🇦Quebec, Canada
Investigational Site Number 124002
🇨🇦Toronto, Canada
Investigational Site Number 152001
🇨🇱Santiago, Chile
Investigational Site Number 152903
🇨🇱Santiago, Chile
Investigational Site Number 152004
🇨🇱Santiago, Chile
Investigational Site Number 152901
🇨🇱Santiago, Chile
Investigational Site Number 152011
🇨🇱Talcahuano, Chile
Investigational Site Number 170009
🇨🇴Bogota, Colombia
Investigational Site Number 152908
🇨🇱Temuco, Chile
Investigational Site Number 152913
🇨🇱Temuco, Chile
Investigational Site Number 152907
🇨🇱Vina Del Mar, Chile
Investigational Site Number 170011
🇨🇴Bogotá, Colombia
Investigational Site Number 170012
🇨🇴Cali, Colombia
Investigational Site Number 170003
🇨🇴Medellin, Colombia
Investigational Site Number 170001
🇨🇴Medellin, Colombia
Investigational Site Number 191502
🇭🇷Slavonski Brod, Croatia
Investigational Site Number 170017
🇨🇴Medellin, Colombia
Investigational Site Number 203005
🇨🇿Brno, Czech Republic
Investigational Site Number 203903
🇨🇿Hradec Kralove, Czech Republic
Investigational Site Number 203901
🇨🇿Praha 2, Czech Republic
Investigational Site Number 250002
🇫🇷Belfort Cedex, France
Investigational Site Number 250016
🇫🇷Avignon Cedex 2, France
Investigational Site Number 250001
🇫🇷Besancon, France
Investigational Site Number 250006
🇫🇷Creteil, France
Investigational Site Number 250012
🇫🇷Montfermeil, France
Investigational Site Number 250005
🇫🇷Mulhouse, France
Investigational Site Number 250014
🇫🇷Strasbourg, France
Investigational Site Number 250011
🇫🇷Pau, France
Investigational Site Number 250008
🇫🇷Toulouse Cedex 9, France
Investigational Site Number 276902
🇩🇪Hamburg, Germany
Investigational Site Number 276006
🇩🇪Frankfurt Am Main, Germany
Investigational Site Number 276018
🇩🇪Rostock, Germany
Investigational Site Number 300011
🇬🇷Athens, Greece
Investigational Site Number 276001
🇩🇪Mainz, Germany
Investigational Site Number 276013
🇩🇪Langen, Germany
Investigational Site Number 300001
🇬🇷Athens, Greece
Investigational Site Number 300008
🇬🇷Larissa, Greece
Investigational Site Number 300005
🇬🇷N. Ionia, Greece
Investigational Site Number 300002
🇬🇷Patras, Greece
Investigational Site Number 300010
🇬🇷Thessaloniki, Greece
Investigational Site Number 348003
🇭🇺Budapest, Hungary
Investigational Site Number 348004
🇭🇺Budapest, Hungary
Investigational Site Number 348007
🇭🇺Szekesfehervar, Hungary
Investigational Site Number 348002
🇭🇺Budapest, Hungary
Investigational Site Number 348001
🇭🇺Szolnok, Hungary
Investigational Site Number 356020
🇮🇳Chandigarh, India
Investigational Site Number 348009
🇭🇺Szeged, Hungary
Investigational Site Number 356008
🇮🇳Bangalore, India
Investigational Site Number 348006
🇭🇺Zalaegerszeg, Hungary
Investigational Site Number 356007
🇮🇳Ahmedabad, India
Investigational Site Number 356012
🇮🇳Allahabad, India
Investigational Site Number 356027
🇮🇳Gurgaon, India
Investigational Site Number 356029
🇮🇳Gurgaon, India
Investigational Site Number 356046
🇮🇳Hyderabad, India
Investigational Site Number 356034
🇮🇳Kolkata, India
Investigational Site Number 356037
🇮🇳Kochi, India
Investigational Site Number 356018
🇮🇳Mangalore, India
Investigational Site Number 356021
🇮🇳Mumbai, India
Investigational Site Number 356022
🇮🇳Nagpur, India
Investigational Site Number 356023
🇮🇳Nagpur, India
Investigational Site Number 356001
🇮🇳New Delhi, India
Investigational Site Number 356033
🇮🇳Pune, India
Investigational Site Number 356024
🇮🇳Secunderabad, India
Investigational Site Number 356044
🇮🇳Vijaywada, India
Investigational Site Number 360501
🇮🇩Depok, Indonesia
Investigational Site Number 356002
🇮🇳Varanasi, India
Investigational Site Number 376005
🇮🇱Afula, Israel
Investigational Site Number 376011
🇮🇱Hadera, Israel
Investigational Site Number 376004
🇮🇱Haifa, Israel
Investigational Site Number 360506
🇮🇩Jakarta, Indonesia
Investigational Site Number 380907
🇮🇹Pescara, Italy
Investigational Site Number 380914
🇮🇹Seriate, Italy
Investigational Site Number 410002
🇰🇷Daegu, Korea, Republic of
Investigational Site Number 440904
🇱🇹Vilnius, Lithuania
Investigational Site Number 604002
🇵🇪Lima, Peru
Investigational Site Number 604014
🇵🇪Lima, Peru
Investigational Site Number 604011
🇵🇪Lima, Peru
Investigational Site Number 616040
🇵🇱Elblag, Poland
Investigational Site Number 616023
🇵🇱Gdansk, Poland
Investigational Site Number 616037
🇵🇱Katowice, Poland
Investigational Site Number 616016
🇵🇱Ostroleka, Poland
Investigational Site Number 616033
🇵🇱Rybnik, Poland
Investigational Site Number 620006
🇵🇹Amadora, Portugal
Investigational Site Number 642002
🇷🇴Brasov, Romania
Investigational Site Number 643025
🇷🇺St-Petersburg, Russian Federation
Investigational Site Number 710005
🇿🇦Cape Town, South Africa
Investigational Site Number 710004
🇿🇦Alberton, South Africa
Investigational Site Number 710002
🇿🇦Kuils River, South Africa
Investigational Site Number 710003
🇿🇦Centurion, South Africa
Investigational Site Number 710007
🇿🇦Pretoria, South Africa
Investigational Site Number 724014
🇪🇸Badalona, Spain
Investigational Site Number 724001
🇪🇸Alicante, Spain
Investigational Site Number 724025
🇪🇸Barcelona, Spain
Investigational Site Number 788001
🇹🇳Tunis, Tunisia
Investigational Site Number 792004
🇹🇷Gaziantep, Turkey
Investigational Site Number 840520
🇺🇸Washington, District of Columbia, United States
Investigational Site Number 840533
🇺🇸New Orleans, Louisiana, United States
Investigational Site Number 032032
🇦🇷Buenos Aires, Argentina
Investigational Site Number 100512
🇧🇬Pazardjik, Bulgaria
Investigational Site Number 100501
🇧🇬Sofia, Bulgaria
Investigational Site Number 203902
🇨🇿Liberec, Czech Republic
Investigational Site Number 203009
🇨🇿Olomouc, Czech Republic
Investigational Site Number 203010
🇨🇿Ostrava - Poruba, Czech Republic
Investigational Site Number 203001
🇨🇿Praha 10, Czech Republic
Investigational Site Number 203003
🇨🇿Praha 5, Czech Republic
Investigational Site Number 203002
🇨🇿Usti Nad Labem, Czech Republic
Investigational Site Number 203007
🇨🇿Praha 5, Czech Republic
Investigational Site Number 356016
🇮🇳Mumbai, India
Investigational Site Number 356011
🇮🇳Mysore, India
Investigational Site Number 356025
🇮🇳New Delhi, India
Investigational Site Number 376013
🇮🇱Jerusalem, Israel
Investigational Site Number 616005
🇵🇱Bialystok, Poland
Investigational Site Number 616047
🇵🇱Radom, Poland
Investigational Site Number 616031
🇵🇱Wloclawek, Poland
Investigational Site Number 616015
🇵🇱Wroclaw, Poland
Investigational Site Number 643011
🇷🇺Kemerovo, Russian Federation
Investigational Site Number 643014
🇷🇺Krasnodar, Russian Federation
Investigational Site Number 643021
🇷🇺Krasnoyarsk, Russian Federation
Investigational Site Number 643024
🇷🇺Novosibirsk, Russian Federation
Investigational Site Number 643013
🇷🇺Samara, Russian Federation
Investigational Site Number 643006
🇷🇺St-Petersburg, Russian Federation
Investigational Site Number 643023
🇷🇺Volgograd, Russian Federation
Investigational Site Number 688505
🇷🇸Belgrade, Serbia
Investigational Site Number 643005
🇷🇺Moscow, Russian Federation
Investigational Site Number 704004
🇻🇳Ho Chi Minh City, Vietnam
Investigational Site Number 704005
🇻🇳Ho Chi Minh City, Vietnam
Investigational Site Number 840166
🇺🇸New Haven, Connecticut, United States
Investigational Site Number 840553
🇺🇸Richmond, Virginia, United States
Investigational Site Number 840188
🇺🇸Richmond, Virginia, United States
Investigational Site Number 840577
🇺🇸Orlando, Florida, United States
Investigational Site Number 840568
🇺🇸Louisville, Kentucky, United States
Investigational Site Number 840194
🇺🇸Kansas City, Missouri, United States
Investigational Site Number 840138
🇺🇸Kansas City, Missouri, United States
Investigational Site Number 840056
🇺🇸Kansas City, Missouri, United States
Investigational Site Number 840059
🇺🇸Omaha, Nebraska, United States
Investigational Site Number 840727
🇺🇸Omaha, Nebraska, United States
Investigational Site Number 840508
🇺🇸Tampa, Florida, United States
Investigational Site Number 840079
🇺🇸Omaha, Nebraska, United States
Investigational Site Number 840203
🇺🇸Austin, Texas, United States
Investigational Site Number 840574
🇺🇸Austin, Texas, United States
Investigational Site Number 344001
🇭🇰Chai Wan, Hong Kong