Skip to main content
Clinical Trials/NCT04144322
NCT04144322
Completed
Not Applicable

Short Dental Implants (5 mm) Versus Long Dental Implants (10 mm) in Combination With Sinus Floor Elevation: A Randomized Clinical Trial

University of Michigan1 site in 1 country34 target enrollmentOctober 14, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Bone Loss, Alveolar
Sponsor
University of Michigan
Enrollment
34
Locations
1
Primary Endpoint
Change in Mesial-distal (M-D) Bone Loss
Status
Completed
Last Updated
12 months ago

Overview

Brief Summary

The purpose of this study is to evaluate the survival rate of 5 mm short implants compared to longer implants (10 mm) placed in sinus-grafted sites.

Primary aim: Compare bone loss between the two groups Secondary aim: Compare surgical time and patient-reported outcomes (satisfaction and post-operative pain)

Detailed Description

34 patients requiring an implant to replace an upper missing tooth in the premolar or 1st molar area with a bone crest height from 5 to 8 mm will be recruited for this trial. Patients will be randomized to either the test (5-mm implant) or control group (10-mm implant) using a computer-generated randomization list . 17 patients will receive a sinus lift procedure, bone graft, and 10 mm implant while the other 17 patients will receive a 5 mm short implant.

Registry
clinicaltrials.gov
Start Date
October 14, 2019
End Date
April 22, 2024
Last Updated
12 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Tae-Ju Oh

Clinical Professor of Dentistry

University of Michigan

Eligibility Criteria

Inclusion Criteria

  • Age 20-70 years at enrollment
  • Systemically healthy patients
  • Full-mouth plaque score and full-mouth bleeding score ≤ 30% (measured at four sites per tooth)
  • In need of one premolar or 1st molar dental implant in the maxillary area
  • Neighboring teeth to the planned implant must have natural root(s) or implant supported restoration.
  • Presence of natural tooth/teeth, partial prosthesis and/or implants in the opposite jaw in contact with the planned crown/s deemed by the investigator as likely to present an initially stable implant situation
  • Residual bone height under the maxillary sinus between 5 to 7 mm and a width of at least 7 mm, as measured on cone beam computer tomography (CBCT) scans.

Exclusion Criteria

  • Unlikely to be able to comply with study procedures
  • Uncontrolled pathologic processes in the oral cavity
  • History of head and neck chemotherapy within 5 years prior to surgery
  • Systemic or local disease or condition that could compromise post-operative healing and/or osseointegration
  • Uncontrolled diabetes mellitus HbA1c \>8
  • Taking corticosteroids, IV bisphosphonates, or any other medication that could influence post-operative healing and/or osseointegration
  • Smokes more than 10 cigarettes/day
  • Present alcohol and/or drug abuser
  • Pregnant, unsure pregnancy status, or lactating females (self-reported)

Outcomes

Primary Outcomes

Change in Mesial-distal (M-D) Bone Loss

Time Frame: Baseline, surgical visit 1 day, 4 months, 5 months, 12 months, 24 months

Comparing mesial-distal (M-D) bone loss between the two groups. This will be measured in millimeters using standardized radiographs of the implant site at the screening visit, surgical visit, 4 months post-op, 5 months post-op, 12 months post-op, and 24 months post-op visits.

Secondary Outcomes

  • Survival Rate(5 month post-op, 12 month post-op, and 24 month post-op visits)
  • Number of Sites With Bleeding on Probing(5 month post-op, 12 month post-op, and 24 month post-op visits)
  • Probing Pocket Depth(5 month post-op, 12 month post-op, and 24 month post-op visits)

Study Sites (1)

Loading locations...

Similar Trials