A comparison of intrathecal 0.5% isobaric ropivacaine and 0.75% isobaric ropivacaine with morphine as adjuvant in lower limb surgeries
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
研究概览
简要总结
This study aims to compare the clinical effectiveness and safety of two concentrations of intrathecal isobaric ropivacaine—0.5% and 0.75%—when used along with morphine as an adjuvant for spinal anesthesia in patients undergoing lower limb surgeries. Participants will be randomly allocated into two groups: one receiving 0.5% isobaric ropivacaine with morphine and the other receiving 0.75% isobaric ropivacaine with morphine.
The study will evaluate the onset and duration of sensory and motor block, quality of intraoperative anesthesia, postoperative analgesia duration, hemodynamic stability, and adverse effects. The objective is to determine which concentration provides better intraoperative conditions and longer, safer postoperative pain relief without increasing side effects. This comparison will help identify the optimal intrathecal dose of isobaric ropivacaine with morphine for lower limb surgeries.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patient giving valid informed consent 2.ASA grade 1 and 2 3.Age between 20 to 60 years 4.Elective lower limb surgeries.
排除标准
- •1.Patient refusal 2.ASA grade 3 and 4 3.Age less than 20 years and more than 60 years 4.Emergency surgeries 5.IHD , Angina, arrythmias,MI 6.Metabolic disorders, neurological ,cardiovascular , congenital diseases 7.Patients allergic to local anesthetic drugs.
研究者
DR Arun Kumar B
Vinayaka missions Kirupanandha Variyar Medical College , Salem - 636308