Randomised Controlled Trial of the Use of Topical Application of Tranexamic Acid in Primary Total Hip Replacement. - (TRANX-H)
- Conditions
- Blood loss in total hip replacement in patient with ostoearthritis and rheumatoid arthritis.
- Registration Number
- EUCTR2009-012141-34-GB
- Lead Sponsor
- niversity Hospital of North Tees and Hartlepool
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
1.Undergoing unilateral primary total hip replacement.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
1.Undergoing unilateral primary total hip replacement for tumour.
2.Allergic to Tranexamic acid.
3.Bleeding tendency (e.g. Haemophilic and platelets disorders).
4.Warfarin, treatment dose of LMWH or conventional heparin).
5.History of DVT and pulmonary embolism.
6.Renal failure with creatinine > 250 micromole/l.
7.Female subjects of child bearing potential must have a negative pregnancy test.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method