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Clinical Trials/NCT01645059
NCT01645059
Completed
N/A

Observational, Cross-sectional, Multicenter Descriptive Study of the Patient Clinical Profile That Begins With Disseminated Her 2 + Breast Cancer or Develops a Metastasis After or During the Adjuvant Therapy (PRIMHER)

Asociación Cacereña para la Investigación y el Desarrollo en Oncología Médica39 sites in 1 country129 target enrollmentJuly 2011

Overview

Phase
N/A
Intervention
Not specified
Conditions
Disseminated HER2+ Breast Cancer
Sponsor
Asociación Cacereña para la Investigación y el Desarrollo en Oncología Médica
Enrollment
129
Locations
39
Primary Endpoint
The Patient Clinical Profile (General Clinical Data and Breast Cancer Characteristics)
Status
Completed
Last Updated
12 years ago

Overview

Brief Summary

This is an observational, cross-sectional study that the main objective is to describe the patient clinical profile that begins with disseminated Her 2+ Breast Cancer or develops a metastasis after or during the adjuvant treatment.

Registry
clinicaltrials.gov
Start Date
July 2011
End Date
March 2013
Last Updated
12 years ago
Study Type
Observational
Sex
Female

Investigators

Sponsor
Asociación Cacereña para la Investigación y el Desarrollo en Oncología Médica
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Women with 18 years or over
  • Patients with disseminated breast cancer histologically or cytological confirmed, who begins with Her 2+ metastatic breast cancer or develops a metastasis after or during the adjuvant therapy
  • Patients treated in first line treatment in metastatic disease.
  • Patients who have positive Her 2 receptor test
  • Patients who have given their written informed consent

Exclusion Criteria

  • Patients who are participating in other studies

Outcomes

Primary Outcomes

The Patient Clinical Profile (General Clinical Data and Breast Cancer Characteristics)

Time Frame: 1 day (there is no follow-up, it is a cross-sectional study)

General clinical data: age, weigh, height, Perfomance Status (ECOG Eastern Cooperative Oncology Group, runs from 0 to 5, with 0 denoting perfect health and 5 death), Breast cancer characteristics: familiar history of breast cancer, initial diagnostic (localized or disseminated), age at diagnostic, TNM (tumor node metástasis), tumor size, node involvement, primary tumor surgery, HER2 overexpression, histological Classification (grades I, II and III,determines the urgency and aggressiveness of treatment, as the higher grades do tend to correspond to poorer survival rates and prognosis), time from the primary breast cancer to distant relapse, description and localization of metastasis

Secondary Outcomes

  • Adjuvant Treatment-Node Affectation(one day (there is no follow-up, it is a cross-sectional study))
  • Adjuvant Treatment in Primary Breast Cancer: Chemotherapy (Treatment With TAC-Docetaxel, Adriamicine and Cyclophosphamide), Hormonal Therapy Anti-HER Biological Therapy(one day (there is no follow-up, it is a cross-sectional study))
  • Disseminated Breast Cancer Treatment-Smoking(one day (there is no follow-up, it is a cross-sectional study))
  • Adjuvant Treatment and Age(one day (there is no follow-up, it is a cross-sectional study))
  • Adjuvant Treatment-Physical Activity(one day (there is no follow-up, it is a cross-sectional study))
  • Disseminated Breast Cancer Treatment-Age(one day (there is no follow-up, it is a cross-sectional study))
  • The Pattern of Treatment in Metastatic Breast Cancer: Chemotherapy, Hormonal Therapy Anti-HER Biological Therapy(one day (there is no follow-up, it si a cross-sectional study))
  • Disseminated Breast Cancer Treatment-physical Activity(one day (there is no follow-up, it is a cross-sectional study))

Study Sites (39)

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