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Clinical Trials/NCT02392715
NCT02392715
Unknown
Not Applicable

Inspiratory Muscle Training Combined With General Exercise Training, Compared to General Exercise Training Alone in Patients With COPD: Randomized Controlled Trial

Hôpital Riviera-Chablais, Vaud-Valais0 sites80 target enrollmentApril 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Obstructive Pulmonary Disease
Sponsor
Hôpital Riviera-Chablais, Vaud-Valais
Enrollment
80
Primary Endpoint
Exercise capacity (six minute walking test)
Last Updated
11 years ago

Overview

Brief Summary

Chronic Obstructive Pulmonary Disease (COPD) is a frequent disease, with increasing prevalence. Pulmonary rehabilitation through general exercise training (GET) is a corner stone of COPD care. Inspiratory muscle training (IMT) as a stand-alone therapy decreases dyspnea and improves exercise capacity. Whether IMT combined with GET adds a supplementary benefit in the rehabilitation of COPD patients is however uncertain.

Detailed Description

Prospective, parallel-group, randomized controlled trial 80 COPD patients will be randomized into two groups. One group will receive general exercise training combined with inspiratory muscle training, 3 times a week, for a total of 36 sessions. The other group will receive general exercise training combined with shame inspiratory muscle training, 3 times a week, for a total of 36 sessions. We will assess the difference of improvement in exercise capacity between the 2 groups with the 6 minute walking test. We will also assess the difference of improvement in quality of life with St-George's respiratory questionnaire. Finally the difference of improvement in maximal inspiratory pressure will be determined. Patients and investigators assessing the outcomes will be blinded to group allocation. Written informed consent will be obtained from each subject. The data will be treated anonymously.

Registry
clinicaltrials.gov
Start Date
April 2015
End Date
December 2016
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Hôpital Riviera-Chablais, Vaud-Valais
Responsible Party
Principal Investigator
Principal Investigator

Stéphanie Vaudan

Stéphanie Vaudan, board-certified respiratory therapist

Hôpital Riviera-Chablais, Vaud-Valais

Eligibility Criteria

Inclusion Criteria

  • COPD demonstrated by spirometry using Gold Criteria
  • Patient referred by a pneumologist to the ambulatory pulmonary rehabilitation program at the Riviera-Chablais Hospital, Monthey
  • Patient with maximal inspiratory pressure \< 60 cmH20
  • Patient older than 40 years

Exclusion Criteria

  • Orthopaedic or neurological troubles that could slant the 6 minute walking test

Outcomes

Primary Outcomes

Exercise capacity (six minute walking test)

Time Frame: 12 weeks

exercise capacity will be assessed by a six minute walking test

Secondary Outcomes

  • Quality of Life (St-George's Respiratory questionnaire)(12 weeks)
  • Maximal inspiratory pressure (MicroRPM by MicroMedical)(12 weeks)

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