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Clinical Trials/NCT06240637
NCT06240637
Recruiting
N/A

Telemonitoring Utility in the Process of Adaptation to Home Mechanical Ventilation

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau1 site in 1 country48 target enrollmentFebruary 17, 2024

Overview

Phase
N/A
Intervention
Not specified
Conditions
Non Invasive Ventilation
Sponsor
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Enrollment
48
Locations
1
Primary Endpoint
Measurement of pCO2 by arterial blood gas
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

The goal of this clinical trial is to evaluate whether telemonitoring, added to the usual process of adaptation to home mechanical ventilation (HMV), achieves a more efficient correction of hypoventilation (reduction of hypercapnia).

Detailed Description

The study population consist of patients with hypercapnic respiratory failure eligible for Home Mechanical Ventilation (HMV) with a total of 48 subjects (24 per group). In those patients with hypercapnic respiratory failure who have an indication for home mechanical ventilation (HMV), without criteria for life support, the initial titration will be performed following the protocol of the Pulmonology Service. After their education, patients will be randomized into one of the following groups: the control group and the telemonitoring group with daily review of Home Mechanical Ventilation (HMV) data. The objectives are to evaluate whether hypoventilation is corrected more efficiently, compare treatment adherence between both groups, analyze unforeseen visits, and assess the number of hospital admissions.

Registry
clinicaltrials.gov
Start Date
February 17, 2024
End Date
December 1, 2026
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Chronic hypercapnic respiratory failure with indication for home mechanical ventilation.
  • Patients who require ventilation with spontaneous-timed mode.
  • Signing of informed consent.

Exclusion Criteria

  • Patient already treated with mechanical ventilation or home CPAP.
  • Patient requiring mechanical ventilation as life support.
  • Pregnancy.
  • Cognitive impairment that makes it impossible to understand the informed consent for the study.
  • Psychiatric pathology that makes compliance with therapy or its follow-up difficult.
  • Impossibility of complying with the protocol.
  • Expected survival less than 12 months.
  • Any other condition that, in the opinion of the researcher, could interfere with the objectives of the study

Outcomes

Primary Outcomes

Measurement of pCO2 by arterial blood gas

Time Frame: 6 months

The partial pressure of carbon dioxide (PCO2) is the measure of carbon dioxide within arterial or venous blood. The moment (day) in which normal pCO2 is detected (pCO2 \< 45 mmHg) will be determined as the success of the therapy.

Secondary Outcomes

  • Adherence(6 months)
  • Unforeseen visits(6 months)
  • Hospital admissions(6 months)

Study Sites (1)

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