Mortality Predictors in Coronary Care in Turkey

Completed

• Conditions: Death, Cardiac

• Registration Number: NCT05296694
• Lead Sponsor: Afyonkarahisar Health Sciences University

Brief Summary

This study was undertaken to investigate and document the mortality rates and predictors in coronary care unit (CCU) patients in Turkey.

It is designed to be a multicenter, observational, cross-sectional, and descriptive study. It will be conducted in 50 centers in 12 regions of Turkey. The study does not include any interventional or treatment procedures.

At the end of the study, clinicians will have up-to-date information about predictors of mortality in CCU patients.

Detailed Description

The MORCOR-TURK study will be conducted as a nationwide registry in 50 tertiary cardiology centers selected from each EuroStat NUTS region in Turkey according to their population sample weight, prioritizing the volume of hospitals in each region. All consecutive patients admitted to the coronary care units (CCU) will be prospectively admitted during a predefined period of 1 month. The study will be conducted by cardiologists in hospitals who regularly treat cardiac patients. Led by the Cardiology Department of Kutahya Evliya Celebi Research and Training Hospital, 50 centers will be included in the study.

There has not been any large-scale epidemiological study on coronary care patients in Turkey recently. Therefore, up-to-date information in this group of patients is lacking. In particular, significant reductions in mortality and morbidity are expected, thanks to improved medical and interventional facilities. In the light of current data, the investigators designed a large-scale study to document mortality rates and predictors in CCU patients.

In this study, the investigators will include consecutive patients admitted to CCU with cardiovascular indications in all participating centers. Patients will be followed and treated by experienced cardiologists and no further experimental intervention will be planned. In the first part of the study, the investigators will record in-hospital mortality rates and try to identify the best predictors. In the second part of the MORCOR-TURK trial which will have a cohort design, the investigators will follow the successfully discharged patients for 1 year. At the end of the follow-up, investigators will assess the risk factors and predictors of cardiovascular events as secondary endpoints.

Study Timeline

• Study First Submitted: 2022-03-08
• Study First Submitted QC: 2022-03-16
• Study First Posted: 2022-03-25
• Study Start: 2022-09-01
• Primary Completion: 2022-10-01
• Study Completion: 2022-10-15
• Status Verified: 2023-01
• Last Update Submitted: 2023-01-31
• Last Update Posted: 2023-02-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2560

Inclusion Criteria

• 18 years of age or older
• hospitalized with cardiovascular diseases
• individuals (or relatives for unconscious patients) who gave written informed consent

Exclusion Criteria

• younger than 18 years of age
• rejecting to sign an informed consent
• hospitalized to CCU by other departments with noncardiac indications
• patients with active severe noncardiac chronic disease (chronic obstructive pulmonary disease, systemic diseases, and malignancy)
• no vital signs despite adequate cardiopulmonary resuscitation during hospitalization
• rejected to stay in CCU and discharged with his/her own request

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
All cause mortality	In-hospital (up to two-weeks)	All types of mortality in-hospital follow up

Trial Locations

Locations (2)

Kutahya Evliya Celebi Research and Training Hospital; 🇹🇷 Kütahya, Turkey

Afyonkarahisar Health Sciences University; 🇹🇷 Afyonkarahisar, Turkey