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Clinical Trials/NCT01529281
NCT01529281
Completed
Not Applicable

Exercise-induced Muscle Damage is Reduced in Resistance Trained Athletes by Branch Chain Amino Acids

Northumbria University0 sites12 target enrollmentStarted: June 2011Last updated:
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ConditionsExercise-induced Muscle Damage

Overview

Phase
Not Applicable
Status
Completed
Enrollment
12
Primary Endpoint
Maximal voluntary contraction
OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsRecords & IdentifiersSimilar Trials

Overview

Brief Summary

It is well documented that exercise-induced muscle damage (EIMD) decreases muscle function and causes severe soreness and discomfort. Branched-chain amino acid (BCAA) supplementation has been shown to increase protein synthesis and decrease muscle protein breakdown, however, the effects of BCAAs on recovery from EIMD are unknown. Thus, the aim of this study was to examine the effects of a BCAA supplement on markers of muscle damage.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Double (Participant, Investigator)

Eligibility Criteria

Ages
18 Years to 30 Years (Adult)
Sex
Male
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •Resistance trained males

Exclusion Criteria

  • •Muscular skeletal disorders

Outcomes

Primary Outcomes

Maximal voluntary contraction

Time Frame: pre exercise, 24 h, 48 h, 72 h, 96 h post-exercise

Isometric MVC of the participants' dominant knee extensors was assessed using a strain gauge. MVCs were performed for 3 s with a 60 s rest between each repetition.

Secondary Outcomes

  • Limb girths(pre-exercise, 24h, 48h, 72h, 96h)
  • Vertical jump(pre-exercise, 24h, 48h, 72h, 96h)
  • Creatine kinase(pre-exercise, 24h, 48h, 72h, 96h)
  • Muscle soreness(pre-exercise, 24h, 48h, 72h, 96h)

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

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