Repeated High-dose Inhaled Corticosteroids for Asthma

Phase 2

Withdrawn

• Conditions: Asthma
• Interventions: Drug: Placebo; Drug: Fluticasone

• Registration Number: NCT00695604
• Lead Sponsor: University of Chicago

Brief Summary

The purpose of this study is to to compare the effects of high-dose Inhaled Corticosteroids (ICS) vs. placebo in adults with chronic stable asthma.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-05
• Study First Submitted: 2008-06-10
• Study First Submitted QC: 2008-06-11
• Study First Posted: 2008-06-12
• Primary Completion: 2011-09
• Study Completion: 2011-09
• Status Verified: 2018-05
• Last Update Submitted: 2018-05-04
• Last Update Posted: 2018-05-08

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	Placebo	Placebo Comparator All patients assigned to this group will receive: 1. Placebo via Metered Dose Inhaler (MDI). 2. Albuterol via MDI.
2	Fluticasone	Active Comparator All patients assigned to this group will receive: 1. Fluticasone via MDI. 2. Albuterol via MDI.

Primary Outcome Measures

Name	Time	Method
Airflow inflammation.	Pre-study and post-study drug administration

Secondary Outcome Measures

Name	Time	Method
Airflow obstruction.	Pre-study and post-study drug administration

Trial Locations

Locations (1)

The University of Chicago; 🇺🇸 Chicago, Illinois, United States