De status van het micromilieu van de (schildwacht)klier en tumor bij patiënten met baarmoederhalskanker.

• Conditions: Cervical cancerLymph nodesHPVCervixcarcinoomLymfeklierenHPV

• Registration Number: NL-OMON22029
• Lead Sponsor: KI-AV

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Other
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

Age ≥ 18 years at start of the study;

- Primary carcinoma of the cervix;

Exclusion Criteria

- Patients with cervical cancer other than squamous,
adeno- or adenosquamous origin.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To analyse the microenvironment of (S)LNs and PT (i.e. antigen presenting cells and other immune cells) and other immune<br /><br>factors produced by the tumour cells in patients with cervical cancer.

Secondary Outcome Measures

Name	Time	Method
- to assess the difference of the microenvironment of tumour-negative and metastatic LNs <br /><br>- to assess the difference of the microenvironment of SLNs and nonSLNs<br /><br>- to analyse the difference in the (S)LNs compared to the primary tumour<br /><br>- to assess the effect of the cervical tumour on the systemic immunity