The Effect of a Lifestyle Intervention Program on Parameters of the Metabolic Syndrome Among Non-Diabetic Obese Arab Women
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Metabolic Syndrome
- Sponsor
- Sheba Medical Center
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- Parameters of the metabolic syndrome
- Status
- Completed
- Last Updated
- 17 years ago
Overview
Brief Summary
The study protocol aims to test the hypothesis that a lifestyle intervention program aimed to increase leisure-time physical activity and reduce body weight will improve the parameters of the metabolic syndrome and quality of life among obese, non-diabetic Arab women
Detailed Description
200 obese non-diabetic Arab women, 35-54 years old, with one or more parameters of the metabolic syndrome (NCEP-III criteria) will be randomized to either conventional or intensive treatment. The intensive intervention arm will include group meetings with physical education instructor (twice a month),group meetings with a dietician (once per month) and personal dietary counselling (once per month). The targets to be achieved will be at least 7% reduction of the initial body weight and engagement in leisure-time sports activity for at least 150 min/week.Evaluation before enrollment and at the end of the trial will include: information on dietary and physical activity habits, quality of life parameters, anthropometric and blood pressure measurement, blood lipid profile, and fasting and post oral glucose load blood glucose and insulin levels. Duration of the intervention: 12 month.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Obesity (BMI: 30-40 kg/squared meter)
- •Female Gender
- •Being 35-54 years old
Exclusion Criteria
- •A contraindication for physical activity
Outcomes
Primary Outcomes
Parameters of the metabolic syndrome
Time Frame: At baseline, and after 6 and 12 months
Secondary Outcomes
- Quality of life(At baseline, and after 12 months)
- Attainment of weight reduction and physical activity targets(At baseline, and after 6 and 12 months)