Evaluation of cognitive function maintenance or improvement effect of propolis
- Conditions
- Adult
- Registration Number
- JPRN-UMIN000036177
- Lead Sponsor
- KSO Corporation
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 90
Not provided
1. Subjects who judged by a doctor as dementia. 2. Subjects who have taken or had taken drugs of dementia or drugs affecting cognitive function 3. Subjects who have current medical history or past medical history of mental disorders (including depressive symptoms) or cerebrovascular diseases. 4. Subjects who regularly use supplements or health foods that may affect cognitive functions. 5. Subjects who judged inappropriate as subjects as a result of clinical examination of screening 1 or brain MRI examination of screening 2. 6. Subjects who were extremely irregular in their lifestyle such as meals or sleeping. 7. Subjects who have a history of asthma or current medical history. 8. Subjects who have allergies to bee products (honey etc.), conifers, trees of Pinaceae, poplar and salicylic acid. 9. Subjects who have history of alcohol dependence or current medical history. 10. Subjects who consume a large amount of alcohol routinely 11. Subjects who have serious illness or medical history such as diabetes, liver disease, kidney disease, heart disease. 12. Subjects who have medical history or history of food allergies or current medical history. 13. Subjects who have take warfarin potassium 14. Subjects who have gerontological depression scale (GDS-S-J) score of 6 or more 15. Subjects who have color vision disorder and can not easily hear people's talk at short distance. 16. Subjects who have problems with the functions of both hands due to injury, surgery, etc. 17. Participating in other food intake, testing using medicines, applying cosmetics and medicines etc, person participating in other studies during participation in this study, consent acquisition within 1 month For other exams Participants 18. Others who judged that the investigator is inappropriate as the subject
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cognitrax (total score of verbal memory, visual memory, finger swing, SDC, stroop, attention shift, persistent processing and 4 part sustained processing) Measuring before intake and 24 weeks after intake.
- Secondary Outcome Measures
Name Time Method MMSE, VAS on forgetfulness and markers related inflammation and heavy metal. Measuring before intake and 24 weeks after intake.