IRCT20210423051054N1尚未招募3 期
Evaluation of therapeutic effect of placental mesenchymal stem cell exosome injection in improving clinical symptoms and MRI changes in patients with knee osteoarthritis
适应症
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 45 years 至 65 years（—）
- 性别
- All
入选标准
- •Pain in both knees over the past 6 months, which is related to the degenerative process of the knee, requires pain medication and has lasted for more than a month.
- •Graphical confirmation of bilateral knee osteoarthritis with grade 2 or 3 based on the Kellgren-Lawrence classification.
- •The knee pain intensity should be greater than or equal to 4 according to the VAS.
排除标准
- •Younger than 45 years or older than 65 years
- •Rheumatic or collagen vascular disease
- •History of malignancy
- •Coagulopathy or taking anticoagulant drug
- •Any injection into the knee joint during the last 3 months
- •A history of recent severe knee trauma in the past 1 month
- •Septic arthritis of the knee or active wound of the knee joint
- •Genovarum or genovalgum greater than 20 degrees
- •Total knee replacement
- •Cardiac pacemaker
- •Cochlear implantation
- •Existence of fragments or foreign metal object in the knee or around the arteries, nerves and brain
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