The effect of exosomes in the treatment of knee osteoarthritis

Phase 3

• Conditions: Knee osteoarthritis.; Bilateral primary osteoarthritis of knee; M17.0

• Registration Number: IRCT20210423051054N1
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 30 May 2022

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Pain in both knees over the past 6 months, which is related to the degenerative process of the knee, requires pain medication and has lasted for more than a month.
Graphical confirmation of bilateral knee osteoarthritis with grade 2 or 3 based on the Kellgren-Lawrence classification.
The knee pain intensity should be greater than or equal to 4 according to the VAS.

Exclusion Criteria

Younger than 45 years or older than 65 years
Rheumatic or collagen vascular disease
History of malignancy
Coagulopathy or taking anticoagulant drug
Any injection into the knee joint during the last 3 months
A history of recent severe knee trauma in the past 1 month
Septic arthritis of the knee or active wound of the knee joint
Genovarum or genovalgum greater than 20 degrees
Total knee replacement
Cardiac pacemaker
Cochlear implantation
Existence of fragments or foreign metal object in the knee or around the arteries, nerves and brain

Study & Design

• Study Type: interventional
• Study Design: Not specified