An explorative study for halting inflammation in patients with emphysema by intravenous administration of autologous bone marrow derived mesenchymal stromal cells. - HEP study

eiden University Medical Center0 个研究点目标入组 30 人开始时间: 2018年4月30日最近更新: 2018年11月26日

试验速览

暂无简介。

•In order to be eligible to participate in this study, a subject must meet all of the following criteria:
•-Age lower than 65;
•-emphysema as reported by a radiologist present in CT images of the lung;
•-gradient of emphysema severity towards the lung apex as assessed by CT-derived lung densitometry by Pulmo CMS software (Medis, NL) and equally distributed between left and right lung;
•-FEV1 between 25% and 45% pred ;
•-TLCO between 30% and 45% pred.;
•-patients in a stable clinical condition.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 30
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•A potential subject who meets any of the following criteria will be excluded from participation in this study:
•-Significant cardiac failure; or active smoking, or
•-< 6 months smoking cessation;
•-or failure to complete pulmonary rehab program before randomization;
•-or women of child bearing potential;
•-or any other condition of the patient that the clinical investigator deemed harmful for study participation.

发起方

eiden University Medical Center