The effect of oil massage therapy along with phototherapy on jaundice in newborns
- Conditions
- Health Condition 1: P58- Neonatal jaundice due to other excessive hemolysisHealth Condition 2: P59- Neonatal jaundice from other and unspecified causes
- Registration Number
- CTRI/2024/03/064576
- Lead Sponsor
- All India Institute of Ayuveda
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Healthy Neonates immediately after birth irrespective of sex and ethnicity
2.Gestational age greater than 28 weeks and birth weight greater than 1500 g
3.An APGAR Score of more than 7 in the first minute.
4.Neonates who do not require oxygen support or positive ventilation or parenteral nutrition.
5.Neonates fulfilling KA87 that is neonatal hyperbilirubinemia clinical features as per ICD 11.
1.Extremely preterm neonates that is less than 1.5 kg
2.Extremely Low Birth Weight that is less than 28 weeks
3.Rhesus and ABO incompatibility and G6PD deficiency.
4.Birth injuries
5.Congenital anomalies
6.Signs of infection or intraventricular or subgaleal hemorrhage
7.Signs of gastrointestinal obstruction or biliary atresia
8.Neonates who are on/require oxygen support/positive ventilation/parenteral nutrition or other intravenous infusions.
9.Neonates expressing hypersensitivity to oil test dose
10.Neonates whose both parents are minors.
11.Mothers receiving drugs narcotic agents/ barbiturates/aspirin/chloral hydrate/reserpine/ phenytoin sodium pre or post parturition.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method owering of total serum bilirubin levels below phototherapy thresholds for the day of life and gestational age following oil massage with Arukaladi tailaTimepoint: Baseline <br/ ><br>Day two <br/ ><br>Day four <br/ ><br>Day six <br/ ><br>Day eight
- Secondary Outcome Measures
Name Time Method Reduction in adverse reactions to phototherapyTimepoint: After phototherapy and at discharge;Reduction in Malondialdehyde and increase in insulin-like growth factor 1 and Glutathione reduced/oxidized ratio (GSH/GSSG ratio) in neonates following oil massage and SNCTimepoint: at birth, after day two, and at discharge;Reduction in salivary cortisol level following oil massage with Bala tailaTimepoint: at birth, after first massage, after day two, and at discharge;Thermoregulation in neonates following oil massage and SNCTimepoint: at birth, after first massage, and daily till discharge