Esthesioneuroblastoma: Outcomes After Treatment
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 试验地点
- 1
- 主要终点
- Quality of Life
研究概览
简要总结
The purpose of this study is to collect and organize data into a repository to gather relevant information for future research from patients diagnosed with a rare malignant sinonasal cancer called esthesioneuroblastoma (ENB) and are scheduled to undergo endonasal skull base surgery. Data being collected includes surgical data, demographics, disease presentation, MRI, CT, PET imaging, and post-operative assessments including pathology tests. After surgery, the investigators will collect chemotherapy and radiation data. Participants will also complete quality of life questionnaires at their follow-up visits.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 10 Years 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Between the age of 10-80 years
- •Diagnosed with esthesioneuroblastoma
排除标准
- •Refusal to participate
结局指标
主要结局
Quality of Life
时间窗: up to 120 months after treatment
Anterior Skull Base (ASB); Skull Base Inventory (SBI); Multidimensional Disease Specific Inventory MDS; ASB-Nasal 12; Sino-Nasal Outcome Test (SNOT-20)
Progression-free survival and overall survival
时间窗: Up to 120 months
Kaplan-Meier survival curves
次要结局
- Length of Hospital Stay(up to 120 months)
- Number of participants with intraoperative complications(up to 120 months)
- Number of participants with postoperative complications(up to 120 months)
- Time spent in operating room(up to 120 months)
- MRI imaging evidence of resection(up to 120 months)
- Surgical Technique(up to 120 months)
研究者
Ricardo L. Carrau, MD
Ricardo L. Carrau, MD
Ohio State University