To determine whether the powered endopath stapler device reduces the incidence of prolonged air leak and duration of chest tube drainage after lung volume reduction surgery
- Conditions
- ung emphysema, chronic obstructive pulmonary diseaseRespiratoryEmphysema, unspecified
- Registration Number
- ISRCTN13216935
- Lead Sponsor
- niversity Hospital Basel
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 20
1. Adult patients with non-bullous pulmonary emphysema were included when they were severely symptomatic despite optimal medical therapy
2. Had severe air flow obstruction (forced expiratory volume in 1 second (FEV1) of 40% of predicted value)
3. Had pulmonary hyperinflation (residual volume (RV) of 200% of predicted value, RV/total lung capacity of 0.60)
4. Minimum age of 18 years
5. Able to consent and indication for bilateral LVRS with a signed informant consent
1. Patients with bullous pulmonary emphysema
2. Severely impaired carbon dioxide diffusing capacity (20% of predicted value)
3. Significant coronary artery disease
4. Under age of 18 years
5. Persons unable to consent and without a signed informant consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> 1. Incidence and volume of air leaks<br> 2. Duration of chest tube drainage of the each side<br>
- Secondary Outcome Measures
Name Time Method <br> 1. Duration and volume of air leak postoperative as well as twice a day, each morning and each afternoon until removal of the chest tubes<br> 2. Operative time, and postoperative complications grade e.g. necessity of reoperation, hospitalisations time<br>