Simultaneous Recording of Cognitive and Motor Functions After Stroke

Completed

• Conditions: Stroke

• Registration Number: NCT05454748
• Lead Sponsor: Centre Hospitalier St Anne

Brief Summary

Aim: To assess whether a cognitively demanding dual-task has greater impact on manual dexterity in chronic stroke patients than in healthy subjects.

Methods: A visuomotor force-tracking task, combining grip force and oculomotor recordings, will be applied in chronic stroke patients with mild-moderate hemiparesis without clinical cognitive impairments and in age-comparable healthy subjects. The dual-task includes avoiding visual distractors and mental addition of numbers. Dual-task effect is calculated as difference in force control accuracy (dual minus single-task) and as difference in saccade rate (addition of numbers minus visual distractors).

Detailed Description

Not available

Study Timeline

• Study Start: 2022-02-03
• Status Verified: 2022-06
• Study First Submitted: 2022-06-27
• Study First Submitted QC: 2022-07-11
• Study First Posted: 2022-07-12
• Primary Completion: 2023-06-20
• Study Completion: 2023-06-20
• Last Update Submitted: 2024-02-29
• Last Update Posted: 2024-03-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• > 18 years old
• First symptomatic stroke more than 3 months ago
• Box and blocks test score < 52
• Mini Mental State Examination Test > 25

Exclusion Criteria

• Psychiatric disease
• Risk of Pregnancy
• History of previous stroke
• Disability that may interfere with the performance of tasks

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Saccade inhibition rate	Baseline measurement (one occasion)	Cross sectional comparison of % of saccades performed towards visual distractors

Trial Locations

Locations (1)

GHU Sainte Anne; 🇫🇷 Paris, France