Assessment Of Different Scores In Predicting Outcome In AECOPD Patients In Emergency Department

Not yet recruiting

• Conditions: Chronic Obstructive Pulmonary Disease

• Registration Number: NCT05793697
• Lead Sponsor: Assiut University

Brief Summary

evaluate the value of different scores in predicting hospital mortality and Need for MV In patients presented to ED with AECOPD.

Detailed Description

Chronic obstructive pulmonary disease (COPD) is one of the top three causes of death worldwide, and 90% of deaths occur in low- and middle-income countries.

Acute exacerbation of chronic obstructive pulmonary disease(AECOPD) is defined as an acute change in patient's dyspnea, cough, or sputum beyond normal variability that is sufficient to warrant a change in therapy. AECOPD has a negative effect on the quality of life, admission and readmission rates, and disease progression.

For these reasons, appropriate management of acute exacerbations is recommended by national and international organizations.

Identifying high-risk dying patients on hospital admission helps in triaging them to the required level of care.

The use of early warning scores in follow-up is recommended for the early detection of critically ill patients and the prediction of clinical deterioration. CURB65, BAP65, qSOFA , DECAF and NEWS, which mainly involve mental status, respiratory rate, oxygen saturations, pulse, blood pressure, age, BUN level, etc., can be used to predict AECOPD-associated mortality in ED given the simple structure and data availability.

Study Timeline

• Study First Submitted: 2022-11-23
• Status Verified: 2023-03
• Study First Submitted QC: 2023-03-30
• Last Update Submitted: 2023-03-30
• Study First Posted: 2023-03-31
• Last Update Posted: 2023-03-31
• Study Start: 2023-05-03
• Primary Completion: 2024-01-03
• Study Completion: 2024-12-03

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 139

Inclusion Criteria

• All patient presented to ED with acute exacerbation of COPD.

Exclusion Criteria

• Patient presented with acute insult affecting other system.
• Patient transferred to other centers.
• Inadequate data.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluate the value of different scores in predicting hospital mortality	one year	Assessment Of Different Scores In Predicting Outcome In Acute Exacerbation Of Chronic Obstructive Pulmonary Disease Patients In Emergency Department as DECAF(dyspnea grade V according to eMRCD,esinopenia\<0.05x10\*9/L,consolidation,acidemia\<7.30,atrial fibrillation); 1=mild,2_3=moderate,4_5=severe can be used to predict AECOPD-associated mortality in ED given the simple structure and data availability.

Secondary Outcome Measures

Name	Time	Method
Value of these scores in predicting need for MV.	one year	Value of these scores in predicting need for MV in AECOPD patient in ER