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Clinical Trials/NCT05793697
NCT05793697
Not yet recruiting
Not Applicable

Assessment Of Different Scores In Predicting Outcome In Acute Exacerbation Of Chronic Obstructive Pulmonary Disease Patients In Emergency Department

Assiut University0 sites139 target enrollmentMay 3, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Obstructive Pulmonary Disease
Sponsor
Assiut University
Enrollment
139
Primary Endpoint
Evaluate the value of different scores in predicting hospital mortality
Status
Not yet recruiting
Last Updated
3 years ago

Overview

Brief Summary

evaluate the value of different scores in predicting hospital mortality and Need for MV In patients presented to ED with AECOPD.

Detailed Description

Chronic obstructive pulmonary disease (COPD) is one of the top three causes of death worldwide, and 90% of deaths occur in low- and middle-income countries. Acute exacerbation of chronic obstructive pulmonary disease(AECOPD) is defined as an acute change in patient's dyspnea, cough, or sputum beyond normal variability that is sufficient to warrant a change in therapy. AECOPD has a negative effect on the quality of life, admission and readmission rates, and disease progression. For these reasons, appropriate management of acute exacerbations is recommended by national and international organizations. Identifying high-risk dying patients on hospital admission helps in triaging them to the required level of care. The use of early warning scores in follow-up is recommended for the early detection of critically ill patients and the prediction of clinical deterioration. CURB65, BAP65, qSOFA , DECAF and NEWS, which mainly involve mental status, respiratory rate, oxygen saturations, pulse, blood pressure, age, BUN level, etc., can be used to predict AECOPD-associated mortality in ED given the simple structure and data availability.

Registry
clinicaltrials.gov
Start Date
May 3, 2023
End Date
December 3, 2024
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mohammed Mostafa Saleh Hussein

Principal investigator

Assiut University

Eligibility Criteria

Inclusion Criteria

  • All patient presented to ED with acute exacerbation of COPD.

Exclusion Criteria

  • Patient presented with acute insult affecting other system.
  • Patient transferred to other centers.
  • Inadequate data.

Outcomes

Primary Outcomes

Evaluate the value of different scores in predicting hospital mortality

Time Frame: one year

Assessment Of Different Scores In Predicting Outcome In Acute Exacerbation Of Chronic Obstructive Pulmonary Disease Patients In Emergency Department as DECAF(dyspnea grade V according to eMRCD,esinopenia\<0.05x10\*9/L,consolidation,acidemia\<7.30,atrial fibrillation) 1=mild,2_3=moderate,4_5=severe can be used to predict AECOPD-associated mortality in ED given the simple structure and data availability.

Secondary Outcomes

  • Value of these scores in predicting need for MV.(one year)

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