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Clinical Trials/NCT06055413
NCT06055413
Completed
N/A

Remote Monitoring to Optimize Ventilatory Support in Children With Invasive Home Mechanical Ventilation

Ann & Robert H Lurie Children's Hospital of Chicago1 site in 1 country50 target enrollmentSeptember 20, 2023

Overview

Phase
N/A
Intervention
Not specified
Conditions
Ventilator Weaning
Sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Enrollment
50
Locations
1
Primary Endpoint
Level of ventilator support
Status
Completed
Last Updated
6 months ago

Overview

Brief Summary

Some children who are born very early or have other congenital conditions may develop severe, long-term lung problems that make them need to use a breathing machine to live at home. There are no studies that identify the best ways to monitor a home breathing machine or adjust its settings. Increasingly, healthcare systems are using information collected at home to make more informed decisions about a patient's healthcare treatment, which is called "remote patient monitoring". This study will ask whether using remote patient monitoring can provide more complete information to a child's team of doctors, nurses, and respiratory therapists to help a child's healthcare team and family make more informed decisions about a child's home ventilator care. The investigators are hypothesizing it can safely decrease the level of breathing support children need while also avoiding emergency and hospital care and supporting their growth, development, and participation in daily life.

Detailed Description

This is a single-arm, non-randomized, open-label trial using remote patient monitoring for chronic management of invasive home mechanical ventilation in children. The investigators hypothesize that integration of longitudinal physiologic data and patient reported outcome measures into routine clinical care over 4 months can optimize home mechanical ventilation use by 1) reducing the level home mechanical ventilation level of support, 2) improving patient and family quality of life, specifically participation in daily activities and patient's lung symptoms, and 3) improving family-reported shared decision-making and child's access to ventilator care. The investigators will also evaluate its usability within family life and provider workflows and assess early implementation outcomes.

Registry
clinicaltrials.gov
Start Date
September 20, 2023
End Date
October 24, 2025
Last Updated
6 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Carolyn Foster

Assistant Professor of Pediatrics

Northwestern University

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Level of ventilator support

Time Frame: 4 months

Liters/kg/day

Secondary Outcomes

  • Quality of life via participation(4 months)
  • Level of shared decision making(4 months)
  • Cessation of awake positive pressure(4 months)
  • Perceived access to ventilator care(4 months)
  • Child growth(4 months)
  • Adoption(4 months)
  • Cessation of positive pressure(4 months)
  • Ventilator management frequency(4 months)
  • Child healthcare utilization(4 months)
  • Lung symptom control(4 months)
  • Reach(4 months)
  • Implementation(4 months)

Study Sites (1)

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