ACTRN12608000297325
Not yet recruiting
Phase 2
The Analgesic Efficacy of Ultrasound Guided Transversus Abdominis Plane (TAP) blocks compared with Placebo in Patients Undergoing Abdominal Surgery
Dr Elizabeth Hessian0 sites52 target enrollmentJune 16, 2008
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Analgesia in patients undergoing abdominal surgery
- Sponsor
- Dr Elizabeth Hessian
- Enrollment
- 52
- Status
- Not yet recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age over 18 years
- •Elective or semi\-elective abdominal surgery requiring mid\-line incision
Exclusion Criteria
- •Patient refusal
- •Acute abdomen
- •A clinical history consistent with opioid tolerance including preoperative opioid consumption of longer than one week, intravenous opioid drug use
- •Preoperative use of opioid antagonists like buprenorphine and naltrexone
- •A clinical history of chronic pain, where patients may benefit from early commencement of agents like ketamine
- •Renal impairment with creatinine clearance less than 60 mL/min
- •Drug allergy or contraindication to morphine, ropivacaine, paracetamol
- •Anaesthetist preference for placement of central neuroaxial blockade/catheter
- •Surgeon refusal to placement of catheters
- •Inability of patient to use patient controlled analgesia pump post\-operatively or to understand grading of pain via verbal pain score
Outcomes
Primary Outcomes
Not specified
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