A prospective, observational, Multicenter study to evAluate safety and effIcacy of cilniDipine, mEtoprolol succinate and chlorthalidoNe in high risk hypertensive patients
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 500
- 试验地点
- 7
- 主要终点
- 1. Reduction in Mean Systolic blood pressure
研究概览
简要总结
This is prospective, observational data collection study of the high risk hypertensive patients visiting various clinics across India. High risk hypertensive patients are generally prescribed more than one antihypertensive drugs. We plan to enroll approximately 500 patients from approximately 25 different clinics receiving treatment of cilnidipine, metoprolol succinate and chlorthalidone. The primary objective of the study is to evaluate reduction in systolic and diastolic blood pressure along with treatment emergent complications and secondary objective of the study is to understand demography, Socioeconomic status of patient, Comorbid conditions, Preferred Dose of cilnidipine, metoprolol succinate and chlorthalidone and associated adverse effects.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 85.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients willing to provide written informed consent form 2.Male or Female patients aged 18 years and above 3.Essential hypertension which is uncontrolled (defined as systolic BP ≥ 140 mmHg or diastolic BP ≥ 90 mmHg ) on dual anti-hypertensive agents 4.Patients treated with cilnidipine, metoprolol succinate and chlorthalidone.
排除标准
- •Patients receiving any other antihypertensive other than cilnidipine, metoprolol succinate and chlorthalidone.
结局指标
主要结局
1. Reduction in Mean Systolic blood pressure
时间窗: 1, 3 and 6 months
2. Reduction in Mean Diastolic blood pressure
时间窗: 1, 3 and 6 months
3. Complications
时间窗: 1, 3 and 6 months
次要结局
- 1.Demographic data of study participants(2.Socioeconomic status of patient)