WiserAD: The effect of a structured online intervention on antidepressant deprescribing in primary care.

Not Applicable

Recruiting

• Conditions: Depression; Inappropriate medicine; Mental Health - Depression; Public Health - Health promotion/education

• Registration Number: ACTRN12622000567729
• Lead Sponsor: niversity of Melbourne

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-04-13
• Last Update Posted: 15 January 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 312

Inclusion Criteria

18-75 years
Stable on AD for >=12m: (no depressive episodes)
No history of recurrent depression
Sufficient English language proficiency to provide informed consent
No or mild depressive symptoms as measured on the Personal Health Questionnaire (PHQ9)
Low risk of Suicide or Self-harm
Agree to consider reviewing their AD use
Agree to be randomized into the study
Willing to provide informed consent

Exclusion Criteria

Those currently experiencing a major life event in the next 3 months
Currently using ADs for any other health condition (other than depression)
Currently using non-SSRI or SNRI ADs, antipsychotics, or other mood stabiliser medication
Have no daily access to the internet

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proportion of patients successfully ceasing ADs at 6 months where successful cessation is defined as a composite of no AD use (as measured by the Resource Use Questionnaire (RUQ)) and the absence of clinically significant depressive symptoms (as measured by the Patient Health Questionnaire-9 (PHQ-9))[ 3-, 6-, 12-, 18-months post completion of baseline. Primary outcome is at 6-months post completion of baseline.]