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The Effect of Patient Cost-Sharing on Antidepressant and Adjunctive Therapy Use

Completed
Conditions
Depressive Disorder, Major
Registration Number
NCT01141400
Lead Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Brief Summary

The primary objective of this study is to measure the effects of patient cost-sharing on the initiation of adjunctive treatment and subsequent healthcare utilization and expenditures among a population of commercially insured adults on antidepressant therapy.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
48865
Inclusion Criteria
  • Adult patients (aged 18-64) will be selected from the MarketScan Commercial Database between January 1, 2004, and September 30, 2008, if they have at least two medical claims with a diagnosis of depression and at least one prescription fill for an antidepressant medication.
Exclusion Criteria
  • Patients who have any claim with a diagnosis of dementia, schizophrenia, delusional disorder, psychoses, pervasive development disorder, mental retardation, cerebral degenerations, Parkinson's disease, senility, manic depression, bipolar disorder, or major depressive disorder with psychotic symptoms.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The primary outcome is any use of adjunctive treatment (combined and by class) and the time to initiation of adjunctive treatment (combined and by class).16 months

16 months of medical and prescription drug coverage after the initial antidepressant prescription claim

Secondary Outcome Measures
NameTimeMethod
sensitivity to cost-sharing will be examined as a function of treatment resistance16 months

16 months of medical and prescription drug coverage after the initial antidepressant prescription claim

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