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Clinical Trials/NCT02803281
NCT02803281
Completed
Not Applicable

Assessment of Patient Frailty Prior to Thoracic Surgery: A Feasibility Study

University Health Network, Toronto3 sites in 1 country40 target enrollmentJuly 29, 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Lung Cancer
Sponsor
University Health Network, Toronto
Enrollment
40
Locations
3
Primary Endpoint
Feasibility Assessment
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Determine the feasibility of assessment of measures of frailty and determine if these measures provide a clinically important contribution of risk assessment in a population of patients undergoing major thoracic surgery for lung or esophageal cancer.

Detailed Description

Both gastro-esophageal and lung cancers are major causes of morbidity and mortality worldwide. In Canada the incidence for Esophageal Adenocarcinoma has doubled in the last two decades, while lung cancer is the leading cause of cancer death. Surgery is a treatment option for these patients; however, esophagectomy in particular, is associated with significant morbidity, mortality and adverse effect on quality of life. Despite satisfactory standard preoperative testing to evaluate risk for surgery, some patients experience morbidity and never recover fully from surgery. Frailty assessment may offer a more sensitive measure of a patient's physiologic reserve, which may allow identification of patients who are poor candidates for surgery. There is a lack of consensus of how best to assess frailty prior to surgery. This study aims to analyze frailty assessment as a tool for patient selection for surgery.

Registry
clinicaltrials.gov
Start Date
July 29, 2015
End Date
November 21, 2018
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients with Esophageal or Lung Cancer who will undergo resectional surgery.

Exclusion Criteria

  • Patients undergoing diagnostic or staging procedures or pulmonary wedge excisions will be excluded.
  • Patients unable to give informed consent

Outcomes

Primary Outcomes

Feasibility Assessment

Time Frame: 2 years

Determine the feasibility of assessment of measures of frailty and determine if these measures provide a clinically important contribution of risk assessment in a population of patients undergoing major thoracic surgery for lung or esophageal cancer.

Study Sites (3)

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