Measurement of Mass Change in Serum Albumin Compared to Serum Lactic Acid as Predictive Tool for Sepsis Prognosis in Non Surgical ICU Patients
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Comparative value between mass change in serum albumin and serum lactate in prediction of sepsis prognosis (discharge or mortality)
研究概览
简要总结
This study aims to assess the reliability of measurement of mass change in serum albumin compared to serum lactic acid as predictive tool for sepsis prognosis in nonsurgical ICU patients
详细描述
This study explores the prognostic value of mass change in serum albumin compared to serum lactic acid levels in non-surgical ICU patients with sepsis. While serum lactate is an established marker of tissue hypo-perfusion and a predictor of sepsis outcomes, serum albumin is less frequently used for dynamic monitoring, although it is known to correlate with severity and mortality
Measurements:
Data Collection:
A-Baseline Data on ICU Admission:
- Demographics: age, sex
- Comorbidities (e.g., diabetes, hypertension, chronic kidney disease)
- Initial hemodynamic parameters (BP-HR-SO2-ECG-UOP-TEMP-RR)
- diagnosis of sepsis involves recognising signs of infection plus organ dysfunction according to SSC and sepsis -3
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults aged ≥18 year 70 years. Diagnosis of sepsis according to survival sepsis campaign(SSC). Patients admitted for medical (non-surgical) conditions.
排除标准
- •Chronic liver disease or cirrhosis. Hyperalbuminuria (ex: nephrotic syndrome, nephritic syndrome). Terminal illness with an expected survival of less than 24 hours. Refusal or inability to obtain informed consent from patients or their care givers.
结局指标
主要结局
Comparative value between mass change in serum albumin and serum lactate in prediction of sepsis prognosis (discharge or mortality)
时间窗: 12 months
Knowing Which is more accurate in predicting the prognosis of sepsis between mass change in serum albumin and serum lactic acid in non surgical icu patients
次要结局
- Duration of vasopressor use and its correlation to prognosis of sepsis.(12months)