IRCT20150210021029N5招募中3 期
Evaluation of the effect of local Atorvastatin gel application on levels of gingival crevicular fluid cytokines IL-17 and TGF-ß in patients with chronic periodontitis and comparison with placebo
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 30 years 至 60 years（—）
- 性别
- All
入选标准
- •Having mild to moderate chronic periodontitis (bone crest distance from CEJ>2, Clinical Attachment Loss=3)
- •Having at least 20 teeth
- •Not having a bridge, crown, or orthodontic braces in the gel application area
- •Having at least 2 pockets with 4-7mm of probing depth and CAL of equal to or greater than 3mm
排除标准
- •Having systemic diseases
- •Nonconformity of the prescribed diet
- •Pregnancy and lactation
- •Showing coronavirus disease symptoms or similar symptoms
- •Receiving periodontal treatment and/or usage of antibiotics during 1 month before treatment
- •Presence of aggressive periodontitis and systemic conditions affecting the periodontal condition
- •Malnutrition and impaired immune status
- •Using statins or allergy to them
- •Using drugs that affect oral tissues
- •Use of antibiotics
- •Use of cholesterol-lowering drugs such as statins
研究者
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