Comparative evaluation of postoperative effects of ozonated water and sodium hypochlorite in endodontic treatment of teeth with symptomatic apical periodontitis : A randomized clinical trial

This study will evaluate the post-operative effects of using ozonated water as an irrigant during single-visit root canal treatment as compared to sodium hypochlorite as an irrigant. Ozonated water in a concentration of 35 microgram/ml will be used as an irrigant during the root canal treatment where conventionally sodium hypochlorite is used. This will be a cross-arch study in which ozonated water will be used as an irrigant in one arch and sodium hypochlorite in the other. The main objective is to evaluate and compare postoperative pain in patients with symptomatic apical periodontitis using 5.25% sodium hypochlorite and ozonated water as an irrigant. Pain will be measured using a Visual analog scale at a baseline of 6hrs, 12hrs, 24hrs, 48hrs,72hrs and 7 days. Ozone is microbicidal, anti-inflammatory, and anti-oxidant. Its positive effects on short-term and long-term basis are to be assessed in this study. The effects of the ozonated water used as an irrigant during root canal treatment is not known. This study will evaluate the effects of ozonated water used as an irrigant during root canal treatment carried out with conventional technique in terms of post-surgical effects such as pain and inflammation.